O68984

PR
Gene name
ppk2
Protein name
Polyphosphate kinase 2
Names
ATP-polyphosphate phosphotransferase 2, Polyphosphoric acid kinase 2
Species
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
KEGG Pathway
cte:CT1049
EC number
2.7.4.1: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

650-714 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O68984

Entry ID Method Resolution Chain Position Source
AF-O68984-F1 Predicted AlphaFoldDB

No variants for O68984

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O68984

No associated diseases with O68984

4 regional properties for O68984

Type Name Position InterPro Accession
domain Polyphosphate kinase middle domain 140 - 342 IPR024953
domain Polyphosphate kinase N-terminal domain 25 - 132 IPR025198
domain Polyphosphate kinase C-terminal domain 2 523 - 693 IPR025200
domain Polyphosphate kinase, C-terminal domain 1 351 - 516 IPR041108

Functions

Description
EC Number 2.7.4.1 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
polyphosphate kinase complex A protein complex that possesses polyphosphate kinase activity.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
polyphosphate kinase activity Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
polyphosphate biosynthetic process The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDSENGTLV PAAIAEPDLR DPLLYVNREL SWIDFNQRVL EEALDSAAHP LLERVKFLSI
70 80 90 100 110 120
FSSNLDEFFM IRVAGLDDQC AAGINERSVD GLTPIEMLER IRERVIGQLR QRNACFFDDI
130 140 150 160 170 180
LPALKRKGIE FVSVSSLSVE QQQLLQHYFR KEVFPVLTPL AFDTGHPFPF MSNLSLNLAI
190 200 210 220 230 240
ELEDEESGAI KFARVKVPGI LSRIIRLDQI EGLGFDDGRI RLLWLEDLVE HNLDQLFPKM
250 260 270 280 290 300
RILQCHPFRI IRDADIEIEE DEAGDLLESI EQGVRSRRYG KVVRLDINPD MPHSIRSLLV
310 320 330 340 350 360
KNLETYERNV YEIGGVLGMS ALMELLKIDR PDLKDELFVP NNPLDDKRTA DIFAEMRSGD
370 380 390 400 410 420
MLLHHPYDSF KPVVDLIWQA ARDPDVLSIK QTLYRVGSNS PVVKALMFAA EQRKQVAVLV
430 440 450 460 470 480
ELKARFDEEN NILWARSLED AGAHVVYGLP GLKTHAKLTM IVRREQEGLR HYLHLGTGNY
490 500 510 520 530 540
NTVTARIYTD YSYLTTDPVL ADDVTELFNS LTGYSKHREY RSLIVSPLNM RRWIMEMIRH
550 560 570 580 590 600
EVDHQKHTGN GRIVMKMNAL VDEEIIRALY RASMAGVKID LAIRGICCLK PGIPGISENI
610 620 630 640 650 660
RVVSVIGRFL EHSRVYYFNN GDHARIFLGS ADIMPRNLDK RVETLFPVIE PRLVESIKSD
670 680 690 700 710
LELTLSDNRK SWEMQPDGTY IRKRGGRPAV DSQRLFMRRS LRRKKNIKKK VKGL