O68823

PR
Gene name
holC (PA3832)
Protein name
DNA polymerase III subunit chi
Names
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA3832
EC number
2.7.7.7: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

39-110 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O68823

Entry ID Method Resolution Chain Position Source
AF-O68823-F1 Predicted AlphaFoldDB

No variants for O68823

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O68823

No associated diseases with O68823

No regional properties for O68823

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O68823

Functions

Description
EC Number 2.7.7.7 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed DNA polymerase activity Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.

2 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
positive regulation of DNA-templated DNA replication initiation Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRVDFYVIP SADPSARLQV ACRLAEKAWR QGMQVYLHCA DEAQRSELDG RLWSFRGEAF
70 80 90 100 110 120
IPHSLAEEDA EAPVALGLGE PPGNHRDLLI NLTLEAPGFV PNFSRVAELV VEEPAIRQAA
130 140
RDKFRFYREQ GYPLQDHRLP RI