O68283

PR
Gene name
eda (PA3181)
Protein name
2-dehydro-3-deoxy-phosphogluconate aldolase
Names
KDPG-aldolase, Phospho-2-dehydro-3-deoxygluconate aldolase, Phospho-2-keto-3-deoxygluconate aldolase
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA3181
EC number
4.1.2.14: Aldehyde-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

47-116 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O68283

Entry ID Method Resolution Chain Position Source
AF-O68283-F1 Predicted AlphaFoldDB

No variants for O68283

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O68283

No associated diseases with O68283

2 regional properties for O68283

Type Name Position InterPro Accession
active_site KDPG/KHG aldolase, active site 1 43 - 52 IPR031337
active_site KDPG/KHG aldolase, active site 2 131 - 144 IPR031338

Functions

Description
EC Number 4.1.2.14 Aldehyde-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
2-dehydro-3-deoxy-phosphogluconate aldolase activity Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHNLEQKTAR IDTLCREARI LPVITIDREA DILPMADALA AGGLTALEIT LRTAHGLTAI
70 80 90 100 110 120
RRLSEERPHL RIGAGTVLDP RTFAAAEKAG ASFVVTPGCT DELLRFALDS EVPLLPGVAS
130 140 150 160 170 180
ASEIMLAYRH GYRRFKLFPA EVSGGPAALK AFSGPFPDIR FCPTGGVSLN NLADYLAVPN
190 200 210
VMCVGGTWML PKAVVDRGDW AQVERLSREA LERFAEHRRH