O67987

PR
Gene name
clcA
Protein name
Chlorocatechol 1,2-dioxygenase
Names
Species
Rhodococcus opacus (Nocardia opaca)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

62-134 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

6 structures for O67987

Entry ID Method Resolution Chain Position Source
1S9A X-ray 247 A A/B 1-257 PDB
3O32 X-ray 285 A A/B 1-257 PDB
3O5U X-ray 235 A A/B 1-257 PDB
3O6J X-ray 290 A A/B 1-257 PDB
3O6R X-ray 260 A A/B 1-257 PDB
AF-O67987-F1 Predicted AlphaFoldDB

No variants for O67987

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O67987

No associated diseases with O67987

2 regional properties for O67987

Type Name Position InterPro Accession
domain Intradiol ring-cleavage dioxygenase, C-terminal 74 - 256 IPR000627
domain Catechol dioxygenase, N-terminal 3 - 63 IPR007535

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
catechol 1,2-dioxygenase activity Catalysis of the reaction: catechol + O2 = cis,cis-muconate.
chlorocatechol 1,2-dioxygenase activity Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.
ferric iron binding Binding to a ferric iron ion, Fe(III).

2 GO annotations of biological process

Name Definition
aromatic compound catabolic process The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
catechol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANTRVIELF DEFTDLIRDF IVRHEITTPE YETIMQYMIS VGEAGEWPLW LDAFFETTVD
70 80 90 100 110 120
SVSYGKGNWT SSAIQGPFFK EGAPLLTGKP ATLPMRADEP GDRMRFTGSV RDTSGTPITG
130 140 150 160 170 180
AVIDVWHSTN DGNYSFFSPA LPDQYLLRGR VVPAEDGSIE FHSIRPVPYE IPKAGPTGQL
190 200 210 220 230 240
MNSYLGRHSW RPAHIHIRIT ADGYRPLITQ LYFEGDPYLD SDSCSAVKSE LVLPVNKIDI
250
DGETWQLVDF NFILQHN