O67898

PR
Gene name
glyS (aq_2141)
Protein name
Glycine--tRNA ligase beta subunit
Names
Glycyl-tRNA synthetase beta subunit, GlyRS
Species
Aquifex aeolicus (strain VF5)
KEGG Pathway
aae:aq_2141
EC number
6.1.1.14: Ligases forming aminoacyl-tRNA and related compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

46-158 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O67898

Entry ID Method Resolution Chain Position Source
AF-O67898-F1 Predicted AlphaFoldDB

No variants for O67898

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O67898

No associated diseases with O67898

1 regional properties for O67898

Type Name Position InterPro Accession
domain DALR anticodon binding 573 - 652 IPR008909

Functions

Description
EC Number 6.1.1.14 Ligases forming aminoacyl-tRNA and related compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
arginine-tRNA ligase activity Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glycine-tRNA ligase activity Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

2 GO annotations of biological process

Name Definition
arginyl-tRNA aminoacylation The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. The arginyl-tRNA synthetase is a class-I synthetase. The activated amino acid is transferred to the 2'-OH group of an alanine accetping tRNA. The 2'-O-aminoacyl-tRNA will ultimately migrate to the 3' position via transesterification.
glycyl-tRNA aminoacylation The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. The glycyll-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a glycine-accepting tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNELLIEIG TEELPAGVIN PALDYLKDKI NSLLNARQVK TYGTPRRLTL YFKDFENERK
70 80 90 100 110 120
EKKEVIWGPP KNVAYDEKGN PTKALEGFLK KNNASLEEVK VLKKDKGEYV AIVRKVIEKS
130 140 150 160 170 180
PIEKLQEEFE EILLSVPFPK RMRWTSSKRI TFSRPVRWIL ALFNGQVLKL RFGELESSNK
190 200 210 220 230 240
TYGHRFLSKG EVTINNPADY EKTLKEHYVI PDFNERKEII LRALEKSSQE VGGKPSYPEG
250 260 270 280 290 300
LVEEVTNLVE YPFPVLGKFD EKYLELPPLV ITTVAAHHQR FFCFEKDGKL LNYFLGISNN
310 320 330 340 350 360
KPNEKIKEGY EKVLRARLED ALFFYREDLK KDLKSLIPEL KKVLFHPKVG SMYEKEERME
370 380 390 400 410 420
KIAQKLCPLL KCEWEKVKEA VWLSKVDLLT EMVKELDELQ GYMGYVYAKA QGYDEEVAKA
430 440 450 460 470 480
LWEQYFPRSL EDKVPETTTG TILSLSDKID NLYSFFKAGE IPKGSSDPYG LRRSAFGIIK
490 500 510 520 530 540
IVDVKNLDLN LEDFKEIYGE FKQYPKLVEF LKQRLISYLE DYPVDIVRAV LNVYSPMEPY
550 560 570 580 590 600
KVINSVRVLY EASKSPEFPS VVEAAKRVIR IIPKDWKNYE VDEKLLSEEA ERELYQKLTE
610 620 630 640 650 660
FENKELKSPL ELLPLKEYID KFFDNVKVMA EDEKIRNNRI SLLKRVENLF RTFGDFNEIV
IKEG