O67588

PR
Gene name
clpB (aq_1672)
Protein name
Chaperone protein ClpB
Names
Species
Aquifex aeolicus (strain VF5)
KEGG Pathway
aae:aq_1672
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-56 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O67588

Entry ID Method Resolution Chain Position Source
AF-O67588-F1 Predicted AlphaFoldDB

No variants for O67588

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O67588

No associated diseases with O67588

10 regional properties for O67588

Type Name Position InterPro Accession
domain UVR domain 603 - 638 IPR001943
domain AAA+ ATPase domain 332 - 476 IPR003593-1
domain AAA+ ATPase domain 718 - 895 IPR003593-2
domain ATPase, AAA-type, core 337 - 467 IPR003959-1
domain ATPase, AAA-type, core 717 - 888 IPR003959-2
domain Clp, repeat (R) domain 3 - 289 IPR004176
conserved_site ClpA/B, conserved site 1 427 - 439 IPR018368
domain Clp ATPase, C-terminal 894 - 983 IPR019489
conserved_site ClpA/B, conserved site 2 752 - 770 IPR028299
domain ClpA/ClpB, AAA lid domain 475 - 575 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

1 GO annotations of biological process

Name Definition
cellular response to heat Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MISENLFSAK SLEYLEKAKE IARENKDTKV DTDHLLIALL LDEKSPLSKY IEKRGIDRKE
70 80 90 100 110 120
FLKRVSEYLE NLNKQLEKAI EAEAQNLINL RTQIMEVKSN IGNVQTELSK IRKAKERILR
130 140 150 160 170 180
ELEYARRYGD WWTAETLELE LRQLEATEQS IRRQLEQVEK SLSTVFAPED VKAFLENKLS
190 200 210 220 230 240
IDGLIRKALE KSPLIEQVKE LGISPDRIID KVAEKVFGKK PTFDYSQYLT QVLEKAQDKA
250 260 270 280 290 300
VSEGEAQVQP SHISAALIEA KDTIGGKLIN QVLGGEKEMK KDVTQELKEE EKSPLERFGV
310 320 330 340 350 360
NLNELARQGK LDPVIGRERE INQVIEILLR RTKNNPVLVG DPGVGKTAIV EGLAQRIVNK
370 380 390 400 410 420
EVPPELQDKE IWSIDMASLL AGSKYRGEFE ERLKALLDEV KEKGNVILFI DEIHTVVGAG
430 440 450 460 470 480
AAEGAVDAAN IMKPALARGE IRVIGATTVD EYRKYIEKDP ALERRFQPVF VDEPTEEQTI
490 500 510 520 530 540
EILKGLRPRL EQFHKVKISD EAIEAAVKLT KRYVTFRRLP DKAIDALDQA AARKKLKVIG
550 560 570 580 590 600
TPPEIQEIER KIKALEEQII EANLKGDYEK EAQLKIEKAK LEKEKQELLG KVGGVEAKIA
610 620 630 640 650 660
ELKKKIEELD EKIKEAAEKG DYEKEAELKI EKAKLEKELK KLEQEKSKEL VVTWDDVAEV
670 680 690 700 710 720
VSEWTGIPVS RLKEEEMQKL LKLEDELHKR VVDQEHAVKA VAEAIRRARA GLKDPKRPIA
730 740 750 760 770 780
SFLFLGPTGV GKTELSKALA ELLFGDEDAL IRLDMSEFKE EHSVAKLIGA PPGYVGYEEG
790 800 810 820 830 840
GKLTEAVRRK PYSVILLDEI EKAHPRVLDL FLQVLDDGRL TDSHGRTVDF RNTVIIMTSN
850 860 870 880 890 900
IGSQYLLNIP VDADEETLNR EFEKAKEKVL EELKLYMRPE FINRIDEIIV FKPLTMRELS
910 920 930 940 950 960
KIIDLLIANV NKRLAERNIK IELTEEAKKE LVRRGYDPAF GARPLKRTIQ KYVETPLADK
970 980 990 1000
IIRGEIKDGM TVVVDYKDGE FVFIPKEEYE KQKAEVSASS EEKKES