O67275
Gene name |
mat (aq_1226) |
Protein name |
Probable S-adenosylmethionine synthase |
Names |
AdoMet synthase, Methionine adenosyltransferase |
Species |
Aquifex aeolicus (strain VF5) |
KEGG Pathway |
aae:aq_1226 |
EC number |
2.5.1.6: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O67275
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O67275-F1 | Predicted | AlphaFoldDB |
No variants for O67275
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O67275 | |||||
No associated diseases with O67275
No regional properties for O67275
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O67275 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.6 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| methionine adenosyltransferase activity | Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| one-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. |
| S-adenosylmethionine biosynthetic process | The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKNIVVTPMT | FEPVYEQDAE | IVERKGIGHP | DTICDYLAEE | LSVALSKLYI | ERFGAIMHHN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VDKALLVGGE | ANPVFGGGEV | ISPIEIYLVG | RALKEYKGVT | IPAEELAIEV | AREWLKDNIR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NLDPDTHVII | KPRIKPGSKD | LVDLFLRFQQ | KGEVPLANDT | SFGVGFAPLD | DLERIVFETE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QLLNSPSFKE | NHPYVGEDIK | VMGVRIKDKV | RITIACAFVS | KYVENIQDYL | EKKEHVRRIV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EEMAQGLTQR | QVEVFINTAD | DPERESVYIT | VTGTSAEQGD | DGQVGRGNRV | NGLITPYRPM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SLEAAAGKNP | VSHIGKIYNV | VANVIADRVV | SEIEEVEEAY | CYLVSQIGKP | INEPQVCDVK |
| 370 | 380 | 390 | |||
| VRTKKDLKSL | EEEIKRIAQE | ELEKMPETWK | KFLNREYAVA |