O67189
Gene name |
aq_1104 |
Protein name |
Uncharacterized protein aq_1104 |
Names |
|
Species |
Aquifex aeolicus (strain VF5) |
KEGG Pathway |
aae:aq_1104 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O67189
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O67189-F1 | Predicted | AlphaFoldDB |
No variants for O67189
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O67189 | |||||
No associated diseases with O67189
1 regional properties for O67189
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA polymerase III delta, N-terminal | 72 - 191 | IPR010372 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| DNA polymerase III complex | The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-directed DNA polymerase activity | Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA-templated DNA replication | A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| METTIFQFQK | TFFTKPPKER | VFVLHGEEQY | LIRTFLSKLK | EKYGENYTVL | WGDEISEEEF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YTALSETSIF | GGSKEKAVVI | YNFGDFLKKL | GRKKKEKERL | IKVLRNVKSN | YVFIVYDAKL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QKQELSSEPL | KSVASFGGIV | VANRLSKERI | KQLVLKKFKE | KGINVENDAL | EYLLQLTGYN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LMELKLEVEK | LIDYASEKKI | LTLDEVKRVA | FSVSENVNVF | EFVDLLLLKD | YEKALKVLDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LISFGIHPLQ | IMKILSSYAL | KLYTLKRLEE | KGEDLNKAME | SVGIKNNFLK | MKFKSYLKAN |
| 310 | 320 | 330 | 340 | ||
| SKEDLKNLIL | SLQRIDAFSK | LYFQDTVQLL | RDFLTSRLER | EVVKNTSHGG |