O67030

PR
Gene name
mnmE
Protein name
tRNA modification GTPase MnmE
Names
Species
Aquifex aeolicus (strain VF5)
KEGG Pathway
aae:aq_871
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

107-243 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O67030

Entry ID Method Resolution Chain Position Source
AF-O67030-F1 Predicted AlphaFoldDB

No variants for O67030

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O67030

No associated diseases with O67030

5 regional properties for O67030

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 216 - 365 IPR005225
domain GTP binding domain 218 - 330 IPR006073
domain GTP-binding protein TrmE, N-terminal 3 - 119 IPR018948
domain MnmE, helical domain 122 - 445 IPR025867
domain TrmE-type guanine nucleotide-binding domain 213 - 370 IPR031168

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
tRNA methylation The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
tRNA wobble uridine modification The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MREPIVAIAT PYGESAIGIV RLSGKGVLDL VKKFFKTKRE IKPRYAHFGV LYDDKGEELD
70 80 90 100 110 120
EGVLIYYKAP HSYTGEDMVE LNLHGNPRIL KRALELFVNA GARLAEPGEF TKRAFLNGKL
130 140 150 160 170 180
DLTQAEAVAE LISAKTELAR KVALKQLHGE LSKHIRPLRE TLLELLAYVE ADIEFAEEDI
190 200 210 220 230 240
PTLTKEQVIQ MVDKVIEGIN ELLKTAKTGK FIREGVKLAI VGRPNVGKSS LFNALLKEER
250 260 270 280 290 300
AIVTDIAGTT RDFIEETLQI KGVPVRLVDT AGIRETKDLV ERIGVERSKQ KVKEADLILF
310 320 330 340 350 360
VIDASQEITE EDLRIYEEIK EKDHIVVANK VDLGIRANLE KFKGEKIVKV SALKGTGLEE
370 380 390 400 410 420
LSEEILKKVG ANLEESVNIY ISVRHETLLK KAKEVLERFK EEFREKDISP EIAMLDLREA
430 440
SDYLGEILGE ITTEDLLGKI FSTFCIGK