O66962
Gene name |
mnmG (gidA, aq_761) |
Protein name |
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG |
Names |
Glucose-inhibited division protein A |
Species |
Aquifex aeolicus (strain VF5) |
KEGG Pathway |
aae:aq_761 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for O66962
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2ZXH | X-ray | 320 A | A/B | 1-617 | PDB |
| 2ZXI | X-ray | 230 A | A/B/C/D | 1-617 | PDB |
| AF-O66962-F1 | Predicted | AlphaFoldDB |
No variants for O66962
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O66962 | |||||
No associated diseases with O66962
5 regional properties for O66962
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | MnmG-related, conserved site | 273 - 287 | IPR020595-1 |
| conserved_site | MnmG-related, conserved site | 368 - 391 | IPR020595-2 |
| domain | tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal | 401 - 615 | IPR026904 |
| domain | MnmG, N-terminal domain | 9 - 399 | IPR040131 |
| domain | tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain | 545 - 616 | IPR047001 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| tRNA methylation | The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule. |
| tRNA wobble uridine modification | The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAWVVDEFDV | VVIGGGHAGI | EAALAAARMG | AKTAMFVLNA | DTIGQMSCNP | AIGGIAKGIV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VREIDALGGE | MGKAIDQTGI | QFKMLNTRKG | KAVQSPRAQA | DKKRYREYMK | KVCENQENLY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IKQEEVVDII | VKNNQVVGVR | TNLGVEYKTK | AVVVTTGTFL | NGVIYIGDKM | IPGGRLGEPR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SEGLSDFYRR | FDFPLIRFKT | GTPARLDKRT | IDFSALEVAP | GDDPPPKFSF | WTEPVGSYWF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PKGKEQVNCW | ITYTTPKTHE | IIRKNLHRTA | LYGGLIKGIG | PRYCPSIEDK | IVKFPDKERH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QIFLEPEGLD | TIEIYPNGLS | TSLPEEVQWE | MYRSIPGLEN | VVLIRPAYAI | EYDVVPPTEL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| YPTLETKKIR | GLFHAGNFNG | TTGYEEAAGQ | GIVAGINAAL | RAFGKEPIYL | RRDESYIGVM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IDDLTTKGVT | EPYRLFTSRS | EYRLYIRQDN | AILRLAKLGR | ELGLLSEEQY | KLVKELEREI |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EKWKEFYKSE | RVSVAVGGDT | RSYSVATLMT | MNYTLDDVKE | KFGYEVPQHP | YVKEEVEIQL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| KYEPYIERER | KLNEKLKKLE | DTKIPPDIDY | DKIPGLTKEA | REKLKKFKPI | TVGQASRIDG |
| 610 | |||||
| ITPAAITALL | VYLGKLD |