O66954
Gene name |
aq_750 |
Protein name |
Bifunctional phosphoglucose/phosphomannose isomerase |
Names |
Glucose-6-phosphate isomerase, GPI, Mannose-6-phosphate isomerase, Phosphoglucose isomerase, PGI, Phosphomannose isomerase, PMI |
Species |
Aquifex aeolicus (strain VF5) |
KEGG Pathway |
aae:aq_750 |
EC number |
5.3.1.8: Interconverting aldoses and ketoses |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O66954
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O66954-F1 | Predicted | AlphaFoldDB |
No variants for O66954
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O66954 | |||||
No associated diseases with O66954
3 regional properties for O66954
Functions
| Description | ||
|---|---|---|
| EC Number | 5.3.1.8 | Interconverting aldoses and ketoses |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| carbohydrate derivative binding | Binding to a carbohydrate derivative. |
| glucose-6-phosphate isomerase activity | Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate. |
| mannose-6-phosphate isomerase activity | Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate derivative metabolic process | The chemical reactions and pathways involving carbohydrate derivative. |
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEVYKVVEG | FYNQFEWEDI | AKDLTPYKGI | VFCGMGGSGI | IGSFASKWLE | HRSFNKPTFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VKDYTLPPFV | DRDYLVFCIS | YSGNTEETLS | NFEEAIGRGI | KPLCITSNGK | LMERAKEEGC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EIYEVPKGFQ | PRYSLGFMLS | KVLNLLGVDK | DELEDAKENL | KENLESLKQK | GKEIANRIYG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YIPVVYSTPL | TAHIAERWKG | QINENSKSPA | YFTILPEMHH | NEVMGWSNPE | LRNKFVYLLM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FDEKDHHRVK | LRVDITKKIL | EDFGVVPIML | KGEGNSYLAR | SLYLVHLADW | VSVFLAELYG |
| 310 | |||||
| YDPVPVKTIE | RIKEELKKHA |