O66809

PR
Gene name
ftsZ
Protein name
Cell division protein FtsZ
Names
Species
Aquifex aeolicus (strain VF5)
KEGG Pathway
aae:aq_525
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

286-367 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for O66809

Entry ID Method Resolution Chain Position Source
2R6R X-ray 170 A 1 1-331 PDB
2R75 X-ray 140 A 1 1-331 PDB
AF-O66809-F1 Predicted AlphaFoldDB

No variants for O66809

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O66809

No associated diseases with O66809

6 regional properties for O66809

Type Name Position InterPro Accession
domain Tubulin/FtsZ, GTPase domain 9 - 207 IPR003008-1
domain Tubulin/FtsZ, GTPase domain 208 - 229 IPR003008-2
domain Tubulin/FtsZ, 2-layer sandwich domain 203 - 321 IPR018316
conserved_site Cell division protein FtsZ, conserved site 40 - 74 IPR020805-1
conserved_site Cell division protein FtsZ, conserved site 93 - 114 IPR020805-2
domain Cell division protein FtsZ, C-terminal 218 - 312 IPR024757

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Assembles at midcell at the inner surface of the cytoplasmic membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

4 GO annotations of biological process

Name Definition
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
protein polymerization The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEEFVNPCKI KVIGVGGGGS NAVNRMYEDG IEGVELYAIN TDVQHLSTLK VPNKIQIGEK
70 80 90 100 110 120
VTRGLGAGAK PEVGEEAALE DIDKIKEILR DTDMVFISAG LGGGTGTGAA PVIAKTAKEM
130 140 150 160 170 180
GILTVAVATL PFRFEGPRKM EKALKGLEKL KESSDAYIVI HNDKIKELSN RTLTIKDAFK
190 200 210 220 230 240
EVDSVLSKAV RGITSIVVTP AVINVDFADV RTTLEEGGLS IIGMGEGRGD EKADIAVEKA
250 260 270 280 290 300
VTSPLLEGNT IEGARRLLVT IWTSEDIPYD IVDEVMERIH SKVHPEAEII FGAVLEPQEQ
310 320 330 340 350 360
DFIRVAIVAT DFPEEKFQVG EKEVKFKVIK KEEKEEPKEE PKPLSDTTYL EEEEIPAVIR
RKNKRLL