O66617

PR
Gene name
aq_257
Protein name
Uncharacterized RNA methyltransferase aq_257
Names
Species
Aquifex aeolicus (strain VF5)
KEGG Pathway
aae:aq_257
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O66617

Entry ID Method Resolution Chain Position Source
AF-O66617-F1 Predicted AlphaFoldDB

No variants for O66617

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O66617

No associated diseases with O66617

3 regional properties for O66617

Type Name Position InterPro Accession
domain TRAM domain 1 - 57 IPR002792
active_site RNA methyltransferase TrmA, active site 354 - 385 IPR030390
conserved_site RNA methyltransferase TrmA, conserved site 406 - 416 IPR030391

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
rRNA (uridine-C5-)-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.

1 GO annotations of biological process

Name Definition
rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKDKPLKLTV EKLVYGGYGF SRLNGKAVFV RFASPKELVE AKVVKEKKDY TEAVVTKVLI
70 80 90 100 110 120
SSPARRKAPC PYYGECGGCQ IQHLNYEEQL RSKKDILLES LERIGKIKEV PYEGEIPSKK
130 140 150 160 170 180
EFNYRVRVQF KIQENRVGFY RWDVKEVVDV EECLLAHERI NELIPHIREV LKVIKDLQEV
190 200 210 220 230 240
HVNYSPTRDE ATLKFVTITH TDEKLLQNIL ENVLPEWVVG IGDYGKVGNS LVKRYKVGRE
250 260 270 280 290 300
HIFMDVGKWQ YRVSNDSFFQ VNYTLWEDFL KEVLDFSESY KKGLDLHCGV GFFTIPLSEQ
310 320 330 340 350 360
GNFIEGADAN PSAIKDAEYN AKINNRDNVI FEEATAFKHL KRRIGEVINL VVVDPPRSGL
370 380 390 400 410 420
LREERDLLLK NKPDKIVYIS CNPTTFARDL KILTKGGYEL KRLKLIDNFP QTYHIESIAL
LEVKD