O64894

PR
Gene name
Acx
Protein name
Acyl-coenzyme A oxidase, peroxisomal
Names
AOX, Long-chain acyl-CoA oxidase
Species
Cucurbita maxima (Pumpkin) (Winter squash)
KEGG Pathway
EC number
1.3.3.6: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-81 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O64894

Entry ID Method Resolution Chain Position Source
AF-O64894-F1 Predicted AlphaFoldDB

No variants for O64894

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O64894

No associated diseases with O64894

3 regional properties for O64894

Type Name Position InterPro Accession
domain Acyl-CoA oxidase, C-terminal 533 - 684 IPR002655
domain Acyl-CoA oxidase/dehydrogenase, middle domain 180 - 296 IPR006091
domain Acyl-CoA dehydrogenase/oxidase C-terminal 328 - 486 IPR009075

Functions

Description
EC Number 1.3.3.6 With oxygen as acceptor
Subcellular Localization
  • Peroxisome
  • Glyoxysome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
glyoxysome A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.

2 GO annotations of molecular function

Name Definition
acyl-CoA oxidase activity Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.
FAD binding Binding to the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.

1 GO annotations of biological process

Name Definition
fatty acid beta-oxidation A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASPGEPNRT AEDESQAAAR RIERLSLHLT PIPLDDSQGV EMETCAAGKA KAKIEVDMGS
70 80 90 100 110 120
LSLYMRGKHR EIQERVFEYF NSRPELQTPV GISMADHREL CMKQLVGLVR EAGIRPFRFV
130 140 150 160 170 180
NEDPAKYFAI MEAVGSVDVS LAIKMGVQFS LWGGSVINLG TKKHRDRFFD GIDNVDYPGC
190 200 210 220 230 240
FAMTELHHGS NVQGLQTTAT FDPITDEFII NTPNDGAIKW WIGNAAVHGK FATVFAKLVL
250 260 270 280 290 300
PTHDSRKTAD MGVHAFIVPI RDLKSHKTLP GIEIHDCGHK VGLNGVDNGA LRFRSVRIPR
310 320 330 340 350 360
DNLLNRFGEV SRDGKYKSSL PSINKRFAAT LGELVGGRVG LAYSSASVLK IASTIAIRYS
370 380 390 400 410 420
LLRQQFGPPK QPEVSILDYQ SQQHKLMPML ASTYAFHFST MQLVEKYAQM KKTHDEELVG
430 440 450 460 470 480
DVHALSAGLK AYVTSYTAKS LSTCREACGG HGYAVVNRFG TLRNDHDIFQ TFEGDNTVLL
490 500 510 520 530 540
QQVAAYLLKQ YQEKFQGGTL AVTWNYLRES MNTYLSQPNP VTARWESADH LRDPKFQLDA
550 560 570 580 590 600
FQYRTSRLLQ SVAVRLRKHT KNLGSFGAWN RCLNHLLTLA ESHIESVILA QFIESVQRCP
610 620 630 640 650 660
NANTQATLKL VCDLYALDRI WNDIGTYRNV DYVAPNKAKA IHKLTEYLCF QVRNIAQELV
670 680
DAFDLPDHVT RAPIAMKSNA YSQYTQYIGF