O64308
Gene name |
|
Protein name |
RNA-directed RNA polymerase subunit beta |
Names |
RNA replicase beta chain |
Species |
Qbeta virus (strain MX1) |
KEGG Pathway |
vg:1261500 |
EC number |
2.7.7.48: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for O64308
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for O64308
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O64308 | |||||
No associated diseases with O64308
3 regional properties for O64308
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 14-3-3 protein, conserved site | 46 - 56 | IPR023409-1 |
| conserved_site | 14-3-3 protein, conserved site | 218 - 237 | IPR023409-2 |
| domain | 14-3-3 domain | 6 - 249 | IPR023410 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.48 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| viral RNA genome replication | The replication of a viral RNA genome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKTLQSRKS | LSGKLRRAAN | TRIVVEGNLA | LSIANDLLSA | LDVEPFNSEE | DCISRSPKFG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ISPDQFRNSY | LRAEIMSKYD | SFSLGINTEA | VAWEKFLAAE | AECAKTNLRL | YRPNYNEDFN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FSLGETCIHM | ARRKIVKLLG | DSVPFEAVLR | HCRFSGGATT | TNSRLYGHPS | FKFALAQECT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PRAVPYVQAL | KACTNMDLGI | TKVSPFNKAV | TVPKNSKTDR | CIAIEPGWNM | FFQLGIGGVI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| REKLHLWNID | LNDQTINQVR | AYSGSCSNEL | ATVDLSSASD | TISLALVELL | LPPAWFKVLT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DLRSRRGMLP | DGRIITYEKI | SSMGNGFTFE | LESLIFAALA | RSLCELLNLQ | PSSVTVYGDD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| IILPSDACSS | LIEVFSYVGF | RTNEKKTFFD | GPFRESCGKH | YFMGVDVTPF | YIRHRIVSPS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DLILVLNQMY | RWATIDGVWD | PRVYPVYTKY | RRLLPDILRR | NVVPDGYGDG | ALVGSVLTSP |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FAENRGWVRR | VPMIIDKKKD | RVRDERGSYL | YELWSLQQLE | CDSEFPFNGS | LVVGTNDGVC |
| 550 | 560 | 570 | 580 | ||
| TYRHRERVST | AISDSVGAYD | IVWIPCSSRV | LAPYGDFRRH | EGSILK |