O62251
Gene name |
F45G2.9 |
Protein name |
rRNA methyltransferase 2, mitochondrial |
Names |
rRNA (uridine-2'-O)-methyltransferase |
Species |
Caenorhabditis elegans |
KEGG Pathway |
cel:CELE_F45G2.9 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O62251
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O62251-F1 | Predicted | AlphaFoldDB |
No variants for O62251
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O62251 | |||||
No associated diseases with O62251
1 regional properties for O62251
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribosomal RNA methyltransferase, FtsJ domain | 32 - 212 | IPR002877 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA methyltransferase activity | Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule. |
| rRNA (uridine-2'-O-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| RNA methylation | Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFSTKKSQGN | LHKYIQRQST | DEFAVKAREH | NYRARSAFKL | IEINEKFKFL | KPESTVIDIG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CAPGSWLQVV | VQKCPNGYAS | GVDLQNVLPI | RGADILSLSD | ITDPAVKLKI | REKLAHRQVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VVLSDMAPNP | TGDNATDHLR | LIELCRSVFR | LFSVENEIEL | VKNGVYLCKI | WDGSARAEFV |
| 190 | 200 | 210 | |||
| RELSDRFSTV | KTVKPTACRD | NSAELYLFCR | NFKK |