O61470
Gene name |
Dox-A2 (AGAP009082) |
Protein name |
Probable 26S proteasome non-ATPase regulatory subunit 3 |
Names |
26S proteasome subunit S3, 26S proteasome regulatory subunit RPN3, Diphenol oxidase A2 component, DOX-A2 |
Species |
Anopheles gambiae (African malaria mosquito) |
KEGG Pathway |
aga:AgaP_AGAP009082 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O61470
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O61470-F1 | Predicted | AlphaFoldDB |
No variants for O61470
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O61470 | |||||
No associated diseases with O61470
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| proteasome regulatory particle, lid subcomplex | The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| enzyme regulator activity | Binds to and modulates the activity of an enzyme. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| regulation of protein catabolic process | Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. |
| ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVSQTAAAAA | PADPIVDVEM | ESAEDAEAAK | KDAELLAVQE | IRDHARQIDK | AVVSKEPRFI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LRVLRSLPTT | RRKLALVVVR | SLAVQLYPAG | PERDGIMAYI | EDYPAGAQEP | ELPRPRAAIK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SPVPEVDAYF | HLLLLVRLLD | KNDLPKATKC | SQDLMAKVVG | QNRRSLDLIA | AKSYFYHSRV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AELNNDLESI | RSFLHSRLRT | ATLRNDFEGQ | AVLINCLLRN | YLHYSLYDQA | DKLVNKSVFP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ETASNNECAR | FLYYLGRIKA | AKLEYSVAHK | QLVQALRKAP | QQAAVGFRQT | VQKLVIVVEL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LLGDIPERKV | FRQAALRRSL | GPYFQLTQAV | RMGNLQRFGE | VLVNFGEQFR | QDHTFTLIIR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LRHNVIKTAI | RSIGLAYSRI | SPQDIARKLG | LDSPEDAEFI | VAKAIRDGVI | EATLDPEKGY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| MRSKESTDIY | STREPQLAFH | QRISFCLDLH | NQSVKAMRYP | PKSYGKELES | AEERREREQQ |
| 490 | |||||
| DLELAKEMAE | EDDDGF |