O60102
Gene name |
rli1 (SPBC14F5.06) |
Protein name |
Translation initiation factor rli1 |
Names |
ATP-binding cassette sub-family E member rli1, RNase L inhibitor |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC14F5.06 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O60102
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O60102-F1 | Predicted | AlphaFoldDB |
No variants for O60102
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O60102 | |||||
No associated diseases with O60102
10 regional properties for O60102
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ABC transporter-like, ATP-binding domain | 70 - 318 | IPR003439-1 |
| domain | ABC transporter-like, ATP-binding domain | 334 - 556 | IPR003439-2 |
| domain | AAA+ ATPase domain | 102 - 296 | IPR003593-1 |
| domain | AAA+ ATPase domain | 374 - 534 | IPR003593-2 |
| domain | RNase L inhibitor RLI-like, possible metal-binding domain | 6 - 37 | IPR007209 |
| conserved_site | ABC transporter-like, conserved site | 220 - 234 | IPR017871-1 |
| conserved_site | ABC transporter-like, conserved site | 456 - 470 | IPR017871-2 |
| domain | 4Fe-4S ferredoxin-type, iron-sulphur binding domain | 46 - 75 | IPR017896 |
| conserved_site | 4Fe-4S ferredoxin, iron-sulphur binding, conserved site | 55 - 66 | IPR017900 |
| domain | RLI, domain 1 | 78 - 335 | IPR034348 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
7 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| iron ion binding | Binding to an iron (Fe) ion. |
| iron-sulfur cluster binding | Binding to an iron-sulfur cluster, a combination of iron and sulfur atoms. |
| ribosomal small subunit binding | Binding to a small ribosomal subunit. |
| ribosome binding | Binding to a ribosome. |
| translation initiation factor activity | Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cytoplasmic translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
| ribosomal large subunit biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis. |
| ribosomal subunit export from nucleus | The directed movement of a ribosomal subunit from the nucleus into the cytoplasm. |
| rRNA processing | Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules. |
| translational initiation | The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. |
| translational termination | The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSESLTRIAI | VSEDKCRPKK | CRQECRRSCP | VVRTGKLCIE | VNPTDRIAFI | SETLCIGCGI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CVKKCPFGAI | NIINLPTNLE | SEVTHRYSAN | SFKLHRLPTP | RPGQVLGLVG | TNGIGKSTAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KILSGKMKPN | LGRYDNPPDW | AEVVKYFRGS | ELQNFFTKVV | EDNIKALIKP | QYVDHIPRAI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KTGDKTVSGL | IKARANNNNF | EEVMDHTDLQ | NLLNREVGHL | SGGELQRFAI | AAVATQKADV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YMFDEPSSYL | DIKQRLKAGR | VIRSLLATTN | YVIVVEHDLS | VLDYLSDFVC | VLYGVPSMYG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VVTLPYSVRE | GINIFLDGHI | PTENLRFRSE | ALTFRLADAS | DEITADRTAE | YNYPDHVIEQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GDFKLTIKSG | GFSDAEIIVL | LGENGTGKTT | FCKWMAKNSD | LKISMKPQTI | APKFQGTVRM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| LFLKKIRAAF | LNGKFQSEVC | KPLSIDNIID | QEVLNLSGGE | LQRVAICLAL | GMPADVYLID |
| 490 | 500 | 510 | 520 | 530 | 540 |
| EPSAYLDSEQ | RIIASKVIRR | FIVNSRKTAF | IVEHDFIMAT | YLADRVILFE | GQPSRDARCN |
| 550 | 560 | 570 | 580 | 590 | |
| PPQSLLTGMN | TFLKNLDVTF | RRDPNTLRPR | INKFDSQMDQ | EQKNAGNYFF | LEN |