O59763

PR
Gene name
oca2
Protein name
Serine/threonine-protein kinase oca2
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPCC1020.10
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-313 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O59763

Entry ID Method Resolution Chain Position Source
AF-O59763-F1 Predicted AlphaFoldDB

No variants for O59763

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O59763

No associated diseases with O59763

3 regional properties for O59763

Type Name Position InterPro Accession
domain Protein kinase domain 302 - 614 IPR000719
active_site Serine/threonine-protein kinase, active site 421 - 433 IPR008271
binding_site Protein kinase, ATP binding site 308 - 331 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
  • Barrier septum
  • Cell tip
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
cell tip The region at the end of the longest axis of a cylindrical or elongated cell.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

6 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
intracellular signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
negative regulation of transcription by RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
protein phosphorylation The process of introducing a phosphate group on to a protein.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.
signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVTPPNVQF NLNGDSDHKS DNSSSSLENK LDTELKITSP PRNPPQRLHP VDFSEHADTD
70 80 90 100 110 120
DDMNHPLPRV QSPVHIKNHI DPKLAEDRYR SSAARHFEPI SIPPSAITSE DEDDYHGSAN
130 140 150 160 170 180
SSTVLPPRTE NALHAASPKP SGSTGYTSPA LSQNSGSGGE GESDEGSFNT QHHRSPIFQA
190 200 210 220 230 240
YPSSEDLVGD PNDPYRRTRR APIKTNPHDI PSQFIFRKLG LHHGKHGHHG HSGSLSLKSL
250 260 270 280 290 300
VPNHHDKHDK HDKHEKHHSS LDLRRFFKSH QKTDKEKKPS VSKSKSSANL QDDHFGLFKK
310 320 330 340 350 360
YGKFGRMLGS GAGGSVRIMK RSSDGKIFAV KEFRARRPTE TEREYARKVT AEFCIGSALH
370 380 390 400 410 420
HTNIIETLDI VEENKKFYEV MEYAPYDMFS IVMSGKMTMP EVYCCFKQLL SGVAYLHSMG
430 440 450 460 470 480
LAHRDLKLDN LVVDSNCFVK IIDFGSAVVF KYPFEADIVE ATGVVGSDPY LAPETLVRKL
490 500 510 520 530 540
YDPRAVDIWS SAIIFCCMAL RRFPWKYPKL SDNSFRLFCM KQPSNDAESP SDILADIKKQ
550 560 570 580 590 600
RLVEQGCEPI RKTDESHSPN SKTDNSSTHK QELYGPWRLL RLLPRETRAV IAHMLELDPV
610 620 630 640
KRYDIHRVFA DNWINDISMC HMENGKVIHS PTHVHNLVAS EESPAPPAKH