O59680
Gene name |
cyt1 (SPBC29A3.18) |
Protein name |
Cytochrome c1, heme protein, mitochondrial |
Names |
Complex III subunit 4, Complex III subunit IV, Cytochrome b-c1 complex subunit 4, Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit, Cytochrome c-1 |
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC29A3.18 |
EC number |
7.1.1.8: Hydron translocation or charge separation linked to oxidoreductase reactions |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O59680
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8Q1B | EM | 340 A | D/O | 1-307 | PDB |
| AF-O59680-F1 | Predicted | AlphaFoldDB |
No variants for O59680
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O59680 | |||||
No associated diseases with O59680
1 regional properties for O59680
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Cytochrome c-like domain | 89 - 259 | IPR009056 |
Functions
| Description | ||
|---|---|---|
| EC Number | 7.1.1.8 | Hydron translocation or charge separation linked to oxidoreductase reactions |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrial respiratory chain complex III | A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| metal ion binding | Binding to a metal ion. |
| ubiquinol-cytochrome-c reductase activity | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mitochondrial electron transport, ubiquinol to cytochrome c | The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFQFVKKKNE | FLKFARLGSR | AFTQNAQKTH | SKGSNIALVS | SSLLSVGMIA | LYYNVYGPSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SAGTPKEEGL | HFIQHDWPQS | KVLSGFDHAS | LRRGFQVYRE | VCSACHSLNL | IAWRHLVGVT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HTADEAKQMA | SEVEYEDGPD | DEGNMFKRPG | KLSDFLPPPY | PNVEAARASN | NGAAPPDLSC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VVRGRHGGQD | YIYSLLTGYT | EPPAGVEVPD | GMNFNPFFPG | TQIAMARPLF | DDAVEFEDGT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PATTAQAAKD | VVNFLHWASE | PELDIRKKMG | FQVITVLTIL | TALSMWYKRF | KWTPIKNRKI |
| FYQRPIK |