Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

5 structures for O59180

Entry ID Method Resolution Chain Position Source
3BK6 X-ray 320 A A/B/C 56-234 PDB
3VIV X-ray 225 A C 234-243 PDB
3WG5 X-ray 240 A C 234-243 PDB
8GN9 X-ray 250 A A 62-170 PDB
AF-O59180-F1 Predicted AlphaFoldDB

No variants for O59180

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O59180

No associated diseases with O59180

1 regional properties for O59180

Type Name Position InterPro Accession
domain Band 7 domain 26 - 205 IPR001107

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMFATNFFVT SIILLFILIF LASAIKIVKE YERAVIFRLG RVVGARGPGL FFIIPIFEKA
70 80 90 100 110 120
VIVDLRTQVL DVPVQETITK DNVPVRVNAV VYFRVVDPVK AVTQVKNYIM ATSQISQTTL
130 140 150 160 170 180
RSVIGQAHLD ELLSERDKLN MQLQRIIDEA TDPWGIKVTA VEIKDVELPA GMQKAMARQA
190 200 210 220 230 240
EAERERRARI TLAEAERQAA EKLREAAEII SEHPMALQLR TLQTISDVAG DKSNVIVLML
250 260
PMEMLKLFKS LSDAAEAYMK KKEEEK