O58762

PR
Gene name
treT
Protein name
Trehalose synthase
Names
Trehalose-synthesizing glycosyltransferase
Species
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
KEGG Pathway
pho:PH1035
EC number
2.4.1.245: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

7 structures for O58762

Entry ID Method Resolution Chain Position Source
2X6Q X-ray 220 A A/B 2-415 PDB
2X6R X-ray 220 A A/B 2-415 PDB
2XA1 X-ray 247 A A/B 2-415 PDB
2XA2 X-ray 250 A A/B 2-415 PDB
2XA9 X-ray 250 A A/B 2-415 PDB
2XMP X-ray 250 A A/B 2-415 PDB
AF-O58762-F1 Predicted AlphaFoldDB

No variants for O58762

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O58762

No associated diseases with O58762

2 regional properties for O58762

Type Name Position InterPro Accession
domain NADPH-dependent FMN reductase-like 13 - 141 IPR005025
domain Flavodoxin/nitric oxide synthase 4 - 190 IPR008254

Functions

Description
EC Number 2.4.1.245 Hexosyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

1 GO annotations of molecular function

Name Definition
trehalose synthase activity Catalysis of the reaction: an NDP-alpha-D-glucose + D-glucopyranose <=> alpha,alpha-trehalose + H+ + a nucleoside diphosphate.

1 GO annotations of biological process

Name Definition
glucose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMYEVKEFSS GKRKLEDYKS IIGEEEVSKI QEKAEKLKGR SFVHVNSTSF GGGVAEILHS
70 80 90 100 110 120
LVPLLRSIGI EARWFVIEGP TEFFNVTKTF HNALQGNESL KLTEEMKELY LNVNRENSKF
130 140 150 160 170 180
IDLSSFDYVL VHDPQPAALI EFYEKKSPWL WRCHIDLSSP NREFWEFLRR FVEKYDRYIF
190 200 210 220 230 240
HLPEYVQPEL DRNKAVIMPP SIDPLSEKNV ELKQTEILRI LERFDVDPEK PIITQVSRFD
250 260 270 280 290 300
PWKGIFDVIE IYRKVKEKIP GVQLLLVGVM AHDDPEGWIY FEKTLRKIGE DYDVKVLTNL
310 320 330 340 350 360
IGVHAREVNA FQRASDVILQ MSIREGFGLT VTEAMWKGKP VIGRAVGGIK FQIVDGETGF
370 380 390 400 410
LVRDANEAVE KVLYLLKHPE VSKEMGAKAK ERVRKNFIIT KHMERYLDIL NSLGG