O57864
Gene name |
cdc6 (PH0124) |
Protein name |
ORC1-type DNA replication protein |
Names |
|
Species |
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
KEGG Pathway |
pho:PH0124 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O57864
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O57864-F1 | Predicted | AlphaFoldDB |
No variants for O57864
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O57864 | |||||
No associated diseases with O57864
2 regional properties for O57864
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ResB-like domain | 30 - 292 | IPR007816-1 |
| domain | ResB-like domain | 307 - 444 | IPR007816-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA replication | The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNEGEQLHLD | QLFEKLLKAR | KIFKNKEVLR | HSYTPKDLPH | RHEQIETLAQ | ILVPVLKGET |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PSNIFVYGKT | GTGKTVTVKF | VTEELKKVSH | KYNIPVDVIY | INCEIVDTHY | RVLANIVNHF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KHETGIEVPL | VGWPTDEVYA | KLKQVIDMRE | RFVIIVLDEI | DKLVKKSGDE | VLYSLTRINT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ELKRAKVSVI | GISNDLKFKE | YLDPRVLSSL | SEEEVVFPPY | DANQLRDILM | QRAEEAFYPG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLDDGVIPLC | AALAAREHGD | ARKALDLLRV | AGEIAEREGA | SKVTEKHVWK | AQEKIEQDMM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EEVIKTLPLQ | SKVLLYAIVL | LDENGELPAN | TGEVYSVYRD | LCEYLDLEPL | TQRRISDLIN |
| 370 | 380 | 390 | 400 | 410 | |
| ELDMLGIINA | KVVSKGRYGR | TKEIRLNVTP | YKIRNVFRYD | YTIQPLLAIS | LKDSQRRLV |