O57742
Gene name |
apgM (PH0037) |
Protein name |
2,3-bisphosphoglycerate-independent phosphoglycerate mutase |
Names |
BPG-independent PGAM, Phosphoglyceromutase, aPGAM |
Species |
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) |
KEGG Pathway |
pho:PH0037 |
EC number |
5.4.2.12: Phosphotransferases (phosphomutases) |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O57742
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2ZKT | X-ray | 240 A | A/B | 1-412 | PDB |
| AF-O57742-F1 | Predicted | AlphaFoldDB |
No variants for O57742
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O57742 | |||||
No associated diseases with O57742
1 regional properties for O57742
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Metalloenzyme | 6 - 401 | IPR006124 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.2.12 | Phosphotransferases (phosphomutases) |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity | Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate. |
| metal ion binding | Binding to a metal ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| glycolytic process | The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVLKRKGLLI | ILDGLGDRPI | KELNGLTPLE | YANTPNMDKL | AEIGILGQQD | PIKPGQPAGS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DTAHLSIFGY | DPYETYRGRG | FFEALGVGLD | LSKDDLAFRV | NFATLENGII | TDRRAGRIST |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EEAHELARAI | QEEVDIGVDF | IFKGATGHRA | VLVLKGMSRG | YKVGDNDPHE | AGKPPLKFSY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EDEDSKKVAE | ILEEFVKKAQ | EVLEKHPINE | RRRKEGKPIA | NYLLIRGAGT | YPNIPMKFTE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| QWKVKAAGVI | AVALVKGVAR | AVGFDVYTPE | GATGEYNTNE | MAKAKKAVEL | LKDYDFVFLH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FKPTDAAGHD | NKPKLKAELI | ERADRMIGYI | LDHVDLEEVV | IAITGDHSTP | CEVMNHSGDP |
| 370 | 380 | 390 | 400 | 410 | |
| VPLLIAGGGV | RTDDTKRFGE | REAMKGGLGR | IRGHDIVPIM | MDLMNRSEKF | GA |