O56860

PR
Gene name
gag
Protein name
Gag polyprotein
Names
Species
Feline foamy virus (FFV) (Feline syncytial virus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

329-452 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for O56860

Entry ID Method Resolution Chain Position Source

No variants for O56860

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O56860

No associated diseases with O56860

No regional properties for O56860

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O56860

Functions

Description
EC Number
Subcellular Localization
  • [Gag protein]: Virion
  • Host nucleus
  • Host cytoplasm
  • Nuclear at initial phase, cytoplasmic at assembly
  • Shortly after infection, Gag protein is targeted to centrosomes
  • It is then actively transported into the nucleus thanks to its nuclear localization signal (By similarity)
  • In the late phases of infection, Gag proteins assemble in the cytoplasm to form the virion's capsids
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
host cell perinuclear region of cytoplasm The host cell cytoplasm situated near, or occurring around, the host nucleus.
host cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic host cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
RNA binding Binding to an RNA molecule or a portion thereof.

3 GO annotations of biological process

Name Definition
microtubule-dependent intracellular transport of viral material towards nucleus The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.
viral entry into host cell The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
viral release from host cell The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARELNPLQL QQLYINNGLQ PNPGHGDIIA VRFTGGPWGP GDRWARVTIR LQDNTGQPLQ
70 80 90 100 110 120
VPGYDLEPGI INLREDILIA GPYNLIRTAF LDLEPARGPE RHGPFGDGRL QPGDGLSEGF
130 140 150 160 170 180
QPITDEEIQA EVGTIGAARN EIRLLREALQ RLQAGGVGRP IPGAVLQPQP VIGPVIPINH
190 200 210 220 230 240
LRSVIGNTPP NPRDVALWLG RSTAAIEGVF PIVDQVTRMR VVNALVASHP GLTLTENEAG
250 260 270 280 290 300
SWNAAISALW RKAHGAAAQH ELAGVLSDIN KKEGIQTAFN LGMQFTDGNW SLVWGIIRTL
310 320 330 340 350 360
LPGQALVTNA QSQFDLMGDD IQRAENFPRV INNLYTMLGL NIHGQSIRPR VQTQPLQTRP
370 380 390 400 410 420
RNPGRSQQGQ LNQPRPQNRA NQSYRPPRQQ QQHSDVPEQR DQRGPSQPPR GSGGGYNFRR
430 440 450 460 470 480
NPQQPQRYGQ GPPGPNPYRR FGDGGNPQQQ GPPPNRGPDQ GPRPGGNPRG GGRGQGPRNG
490 500 510
GGSAAAVHTV KASENETKNG SAEAVDGGKK GGKD