O52762
Gene name |
katA (PA4236) |
Protein name |
Catalase |
Names |
|
Species |
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
KEGG Pathway |
pae:PA4236 |
EC number |
1.11.1.6: Peroxidases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for O52762
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4E37 | X-ray | 253 A | A/B/C/D | 3-482 | PDB |
| AF-O52762-F1 | Predicted | AlphaFoldDB |
No variants for O52762
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O52762 | |||||
No associated diseases with O52762
Functions
| Description | ||
|---|---|---|
| EC Number | 1.11.1.6 | Peroxidases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| catalase activity | Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O. |
| heme binding | Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring. |
| metal ion binding | Binding to a metal ion. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| hydrogen peroxide catabolic process | The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2). |
| response to hydrogen peroxide | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEEKTRLTTA | AGAPVVDNQN | VQTAGPRGPM | LLQDVWFLEK | LAHFDREVIP | ERRMHAKGSA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AYGTFTVTHD | ITPYTRAKIF | SQVGKKTDMF | LRFSTVAGER | GAADAERDIR | GFSMRFYTEQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GNWDLVGNNT | PVFYLRDPLK | FPDLNHVVKR | DPRTNLRNAT | FKWDFFSHLP | ESLHQLTIDF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SDRGLPKSYR | HIHGFGSHTF | SFINANNERF | WVKFHFKTQQ | GIENLTNAEA | AEVIAQDRES |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SQRDLYESIE | KGDFPRWKMY | VQIMPEKEAA | TYRYNPFDLT | KVWPHGDYPL | IEVGFFELNR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| NPDNYFAEVE | QAAFTPANVV | PGIGFSPDKM | LQGRLFSYGD | AHRYRLGVNH | HQIPVNAARC |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PHQVYHRDGG | MRVDGNNAHQ | RVTYEPNSFN | QWQEQPDFSE | PPLSLEGAAD | HWNHRVDDDY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| YSQPAALFHL | FTDEQKQRLF | ANIAEDIRDV | PEQIQRRQIG | LFLKVDPAYG | KGVADALGLK |
| LD |