Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O52351

Entry ID Method Resolution Chain Position Source
AF-O52351-F1 Predicted AlphaFoldDB

No variants for O52351

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O52351

No associated diseases with O52351

2 regional properties for O52351

Type Name Position InterPro Accession
conserved_site SecY conserved site 80 - 99 IPR030659-1
conserved_site SecY conserved site 178 - 195 IPR030659-2

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
protein transport by the Sec complex The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKTNSKNLL GQKIIKLLRN RDFVISVFVT LFLILLFRVI SVIPLPGITI SQNKNNLNNG
70 80 90 100 110 120
VSDFFDLFNL LGGGGLSQLS LFAVGISPYI SAQIIMQLLS TDLIPPLSKL AKSGELGRRR
130 140 150 160 170 180
IELITRFVTL PFAVVQAFAI IALINNQRNG AIRFENGGIL HQAFYIVTMT AGTYIGIFIG
190 200 210 220 230 240
DIISKKGVGN GITLLILSGI LARLPDGFIV MYRVLGGVII STNPILTSAI NFSLYFLAFL
250 260 270 280 290 300
VLLLAISFVN SSTRRIPIQQ TGEGMVLGNE KLPYLPIKLN AAGVIPVIFA SSIMSIPITI
310 320 330 340 350 360
AEFQPQSEAR WFVEDYLSLR TPVGISLYVI LIIIFTFFYS YIQINPEQLA ENFNKSHKFI
370 380 390 400 410 420
PGVRPGLDTE KHITKVLMRI NFIGAPFLAI VAVIPYIISL VLNVPTTLSL GGTGIIIMVS
430 440 450 460 470 480
ASMELYRSLR SAATTTSYQR LRKDIANRIE AELSLNDYMN KPNLEHDQYG LLGQHKKVEP
490
TQDKKKNPSD PLEVSQLW