O50087

PR
Gene name
nep1 (PH1379)
Protein name
Ribosomal RNA small subunit methyltransferase Nep1
Names
16S rRNA (pseudouridine-N1-)-methyltransferase Nep1
Species
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
KEGG Pathway
pho:PH1379
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O50087

Entry ID Method Resolution Chain Position Source
AF-O50087-F1 Predicted AlphaFoldDB

No variants for O50087

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O50087

No associated diseases with O50087

2 regional properties for O50087

Type Name Position InterPro Accession
domain FeS cluster biogenesis 17 - 112 IPR000361
domain NIF system FeS cluster assembly, NifU, C-terminal 127 - 198 IPR001075

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
rRNA (pseudouridine) methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
rRNA binding Binding to a ribosomal RNA.

1 GO annotations of biological process

Name Definition
rRNA base methylation The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEEKKRLHLI IADAELETVP PEILDHPAIV NYAKRRKKRP EKIILDSTYH HAALRQLEDG
70 80 90 100 110 120
ERRGRPDIVH ICLLNALDSI LNKEDRLRVY VHTRNDYVIY IKPETRLPRN YNRFIGLMEN
130 140 150 160 170 180
LFEKGAVPED LELLRMEKKT LNELIEEINP DVVFIMHEEG ELMIPKNFGK LLDKFKKPTV
190 200 210 220
IVGGFPHGDF KSKVDGVKIS LYREPLMAWT IVNEVIVSYE WEVIKKFKS