O49506
Gene name |
GLO5 (GOX3, At4g18360, F28J12.20) |
Protein name |
Glycolate oxidase 3 |
Names |
GOX 3, AtGLO5, Peroxisomal (S)-2-hydroxy-acid oxidase GLO5, Short chain alpha-hydroxy acid oxidase GLO5 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G18360 |
EC number |
1.1.3.15: With oxygen as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O49506
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O49506-F1 | Predicted | AlphaFoldDB |
28 variants for O49506
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_10148383_C_T | 2 | E>K | No | 1000Genomes | |
| tmp_4_10148382_T_A | 2 | E>V | No | 1000Genomes | |
| tmp_4_10148344_C_T | 15 | E>K | No | 1000Genomes | |
| tmp_4_10148340_T_A | 16 | K>I | No | 1000Genomes | |
| ENSVATH02873406 | 34 | T>S | No | 1000Genomes | |
| ENSVATH06714397 | 53 | I>F | No | 1000Genomes | |
| ENSVATH00519631 | 61 | S>T | No | 1000Genomes | |
| tmp_4_10148098_C_G | 66 | G>R | No | 1000Genomes | |
| tmp_4_10147886_C_T | 99 | A>T | No | 1000Genomes | |
| ENSVATH06714393 | 100 | G>R | No | 1000Genomes | |
| tmp_4_10147759_A_T | 111 | C>* | No | 1000Genomes | |
| ENSVATH06714389 | 111 | C>S | No | 1000Genomes | |
| ENSVATH06714388 | 115 | E>D | No | 1000Genomes | |
| tmp_4_10147734_C_T | 120 | G>R | No | 1000Genomes | |
| tmp_4_10147733_C_A | 120 | G>V | No | 1000Genomes | |
| tmp_4_10147612_C_T | 136 | V>M | No | 1000Genomes | |
| ENSVATH11972916 | 143 | R>Q | No | 1000Genomes | |
| ENSVATH02873392 | 146 | E>D | No | 1000Genomes | |
| tmp_4_10147582_C_G | 146 | E>Q | No | 1000Genomes | |
| tmp_4_10147366_C_G | 192 | D>H | No | 1000Genomes | |
| tmp_4_10147092_C_T | 224 | S>N | No | 1000Genomes | |
| ENSVATH06714382 | 248 | G>A | No | 1000Genomes | |
| tmp_4_10146740_C_T | 278 | G>S | No | 1000Genomes | |
| tmp_4_10146329_C_T | 307 | V>I | No | 1000Genomes | |
| ENSVATH02873364 | 329 | M>I | No | 1000Genomes | |
| ENSVATH00519622 | 352 | T>N | No | 1000Genomes | |
| tmp_4_10146181_G_A | 356 | T>I | No | 1000Genomes | |
| ENSVATH00519620 | 365 | S>L | No | 1000Genomes |
No associated diseases with O49506
No regional properties for O49506
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O49506 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.3.15 | With oxygen as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| (S)-2-hydroxy-acid oxidase activity | Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide. |
| FMN binding | Binding to flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to bacterium | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
| hydrogen peroxide biosynthetic process | The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA. |
| oxidative photosynthetic carbon pathway | The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2). |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEITNVMEYE | KIAKEKLPKM | VYDYYASGAE | DQWTLQENRN | AFSRILFRPR | ILIDVSKIDV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STTVLGFNIS | MPIMIAPTAM | QKMAHPDGEL | ATARATSAAG | TIMTLSSWAT | CSVEEVASTG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PGIRFFQLYV | YKDRNVVIQL | VKRAEEAGFK | AIALTVDTPR | LGRRESDIKN | RFALPRGLTL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KNFEGLDLGK | IDKTNDSGLA | SYVAGQVDQS | LSWKDIKWLQ | SITSLPILVK | GVITAEDARI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AVEYGAAGII | VSNHGARQLD | YVPATIVALE | EVVKAVEGRI | PVFLDGGVRR | GTDVFKALAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GASGVFVGRP | SLFSLAADGE | AGVRKMLQML | RDEFELTMAL | SGCRSLREIS | RTHIKTDWDT |
| PHYLSAKL |