O48882

PR
Gene name
ACO2
Protein name
1-aminocyclopropane-1-carboxylate oxidase 2
Names
ACC oxidase 2, Ethylene-forming enzyme, EFE
Species
Malus domestica (Apple) (Pyrus malus)
KEGG Pathway
EC number
1.14.17.4: With reduced ascorbate as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

24-110 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O48882

Entry ID Method Resolution Chain Position Source
AF-O48882-F1 Predicted AlphaFoldDB

No variants for O48882

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O48882

No associated diseases with O48882

3 regional properties for O48882

Type Name Position InterPro Accession
domain Oxoglutarate/iron-dependent dioxygenase 153 - 253 IPR005123
domain Non-haem dioxygenase N-terminal domain 5 - 95 IPR026992
domain Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain 159 - 253 IPR044861

Functions

Description
EC Number 1.14.17.4 With reduced ascorbate as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
1-aminocyclopropane-1-carboxylate oxidase activity Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.
L-ascorbic acid binding Binding to L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
ethylene biosynthetic process The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
fruit ripening An developmental maturation process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATFPVVDMD LINGEERAAT LEKINDACEN WGFFELVNHG ISTELLDTVE KMNKDHYKKT
70 80 90 100 110 120
MEQRFKEMVA AKGLEAVQSE IHYLDWESTF FLRHLPSSNI SEIPDLEEDY RKTMKEFAVE
130 140 150 160 170 180
LEKLAEKLLD LLCENLGLEK GYLKKAFYGS KGPNFGTKVS NYPPCPKPDL IKGLRAHTDA
190 200 210 220 230 240
GGIILLFQDD KVSGLQLLKD GEWMDVPPVH HSIVINLGDQ IEVITNGKYK SIMHRVIAQS
250 260 270 280 290 300
DGTRMSIASF YNPGDDAFIS PAPALLEEKS EVSPTYPKFL FDDYMKLYSG LKFQAKEPRF
310 320
EAMKARETTP VETARGLRAV RWNTTKRNQN