O46683

PR
Gene name
Protein name
Mast cell protease 3
Names
sMCP-3
Species
Ovis aries (Sheep)
KEGG Pathway
oas:443429
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O46683

Entry ID Method Resolution Chain Position Source
AF-O46683-F1 Predicted AlphaFoldDB

No variants for O46683

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O46683

No associated diseases with O46683

3 regional properties for O46683

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 46 - 56 IPR023409-1
conserved_site 14-3-3 protein, conserved site 218 - 237 IPR023409-2
domain 14-3-3 domain 6 - 249 IPR023410

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Cytoplasmic granule
  • Secretory granules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVLFLLLVAL LSPAGEAGKI IGGHEAKPHS RPYMAFLQFK ISGKSYICGG FLVREDFVLT
70 80 90 100 110 120
AAHCLGSSIN VTLGAHTITD QERTQQVIQV RRAIPHPDYN DETCANDIML LQLTRKAEMT
130 140 150 160 170 180
DAVSLINLPR SLEKVKPGMM CSVAGWGQLG VNMPSADKLQ EVDLEVQREE KCIARFKDYI
190 200 210 220 230 240
PVTQICAGDP SKRKDSFLGD SGGPLVCDGV AQGIVSYGKD DGTTPNVYTR ISSFLSWIQR
250
TMRQYKNQGS A