O46578

PR
Gene name
COX4I1 (COX4)
Protein name
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
Names
Cytochrome c oxidase polypeptide IV, Cytochrome c oxidase subunit IV isoform 1, COX IV-1
Species
Gorilla gorilla gorilla (Western lowland gorilla)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O46578

Entry ID Method Resolution Chain Position Source
AF-O46578-F1 Predicted AlphaFoldDB

No variants for O46578

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O46578

No associated diseases with O46578

No regional properties for O46578

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O46578

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
mitochondrial inner membrane The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
mitochondrial respiratory chain complex IV A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
mitochondrial electron transport, cytochrome c to oxygen The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
SVVKSEDFSL PAYMDRRDYP LPEVAHVKHL SASQKALKEK EKASWSSLSM DEKVELYRIK
70 80 90 100 110 120
FKESFAEMNR GSNEWKTVVG GAMFFIGFTA LVIMWQKHYV YGPLPQSFDK EWVAKQTKRM
130 140
LDMKVNPIQG LASKWDYEKN EWKK