O45503

PR
Gene name
mtx-1 (F39B2.11)
Protein name
Metaxin-1 homolog
Names
Mitochondrial outer membrane import complex protein 1
Species
Caenorhabditis elegans
KEGG Pathway
cel:CELE_F39B2.11
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

222-300 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O45503

Entry ID Method Resolution Chain Position Source
AF-O45503-F1 Predicted AlphaFoldDB

No variants for O45503

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O45503

No associated diseases with O45503

3 regional properties for O45503

Type Name Position InterPro Accession
domain Glutathione S-transferase, C-terminal-like 86 - 247 IPR010987
domain Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain 19 - 144 IPR019564
domain Metaxin, glutathione S-transferase domain 166 - 225 IPR033468

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion outer membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
SAM complex A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q13505 MTX1 Metaxin-1 Homo sapiens (Human) PR
10 20 30 40 50 60
MELHIWPSDF GLPTIDVVSL QFLACSKMCA SPVRVIQSTR PWRSPSGELP MVAQTEGEAK
70 80 90 100 110 120
PVTDFEKFVD ILKKCGQDVV IDADLTTIEK AQLDAFSCYL HHNLYPAVMH TFWTDELNYN
130 140 150 160 170 180
TVTQYWYASH LHFPYNLYYL EKRRKKALRL LAGKNDTEIL KEAFMALNTL STKLGDNKFF
190 200 210 220 230 240
CGNKPTSLDA LVFGYLAPLL RVPLPNDRLQ VQLSACPNLV RFVETVSSIY LPLGEDELKR
250 260 270 280 290 300
QQANRKMWQS RISKAKADKE AAKTTEEASE SLPEEPPMRD AILFTLGALT LSLVFAIHTG
310
LIQVSVEEEI SE