O43081
Gene name |
SPBC947.06c |
Protein name |
Uncharacterized MFS-type transporter C947.06c |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC947.06c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O43081
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O43081-F1 | Predicted | AlphaFoldDB |
No variants for O43081
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O43081 | |||||
No associated diseases with O43081
1 regional properties for O43081
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Major facilitator superfamily domain | 58 - 487 | IPR020846 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| spermidine transmembrane transporter activity | Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of a membrane to the other. |
| spermine transmembrane transporter activity | Enables the transfer of spermine from one side of a membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| spermidine transmembrane transport | The process in which spermidine is transported across a membrane. |
| spermine transmembrane transport | The process in which spermine is transported across a membrane. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKENDHLNSV | SSSEIEKCDE | DVEEELYSYP | DSDFLVTFNG | EDDPEKPLNW | PVSIKLLNTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LYGLTTFAAQ | FNSTTMSPTT | SHLVNAYPIG | HEVAVLPTCL | YILGIAFGPM | IFAPFSEVNG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RKIGVLVPFF | LSILFTIGTA | SSDSVAAIMC | TRFFAGLFAG | APVVSSGGVM | ADLWCPAQRG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TALIFYAFFV | VSGADFGPII | SSLVTEHSDT | AWRWPLWTIV | IIECFILTLD | VFLIKETFGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VILATKAKNL | RLTTKNWGLH | AAHDEYRLDF | KEFVTLHLVR | PFAMLATPIV | FFIAMFASYV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YGILYLVLTT | IPYTFGMTKN | WQGTISTLPM | IAMFTGVVIG | GSFNIMWNQR | YAKLITANGG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KPLPEQRLPL | MMAVGWLMPA | GIFVFAWTNS | PNIHWIAPFI | GISMMGAGFF | VIFQGCLNYL |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VDTFTKFAAS | AIAANTFTRS | IFAGTFPLFS | EIMFKKLGVH | WGGSLVGFIA | LGMIPIPFIF |
| 490 | |||||
| YMMGDKLRRK | NRFIKLIT |