O43042

PR
Gene name
mrpl3 (SPBC3B9.14c)
Protein name
54S ribosomal protein L3, mitochondrial
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC3B9.14c
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O43042

Entry ID Method Resolution Chain Position Source
AF-O43042-F1 Predicted AlphaFoldDB

No variants for O43042

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O43042

No associated diseases with O43042

3 regional properties for O43042

Type Name Position InterPro Accession
domain Ribonuclease III domain 47 - 211 IPR000999
domain Double-stranded RNA-binding domain 217 - 285 IPR014720
domain 54S ribosomal protein L3, double-stranded RNA binding domain 204 - 287 IPR044443

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrial large ribosomal subunit The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

3 GO annotations of molecular function

Name Definition
double-stranded RNA binding Binding to double-stranded RNA.
ribonuclease III activity Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

3 GO annotations of biological process

Name Definition
mitochondrial translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFISRSTTT FRRSISMKDY ARVRWYSNSG KSLIENILSS KIAISKVYTL KKRIGLPESY
70 80 90 100 110 120
PMKVLVQALI DKTVVQNPQY SNEKLWSIGK VFGDFYVLEY IKCKYPRLPE EAVHGMQNGW
130 140 150 160 170 180
MGSKALSQLA TIWGLEVQRR EEGLQESFGK VLAKRADPEM LRKPGEIYKD EAARRAILAI
190 200 210 220 230 240
LGGVYLHQGF NDTKKFINDH ILSKQLDPRT MLQLQWPRRQ LSRLCKRLSL KEPVYRIIAE
250 260 270 280 290 300
TGRKSREPVF VIGAYSGHHL LGQGQASSLN LAEQQAAYNS LISYYIHSPP FRQLPSDYLE
310 320
VNDGKIPKAS EPYTSIPLVS HGQLVI