Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O43000
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O43000-F1 | Predicted | AlphaFoldDB |
No variants for O43000
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O43000 | |||||
No associated diseases with O43000
1 regional properties for O43000
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | YqgF/RNase H-like domain | 1 - 103 | IPR006641 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| intrinsic component of membrane | The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| pantothenate transmembrane transporter activity | Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods. |
| transmembrane transporter activity | Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| pantothenate import across plasma membrane | The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MALLNRLAKT | FSPYYGLNKV | EQKLLIKIDW | FILSYCCVSY | FINYLDRSSI | NNAYLSGMQE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DLKMHGNELQ | DINVVFTCGY | IIGQLPGSYA | LQRVPARLWF | SVMNILWGLM | TIFSFAVHSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RALMILRFFM | AVAEASTFAG | THYILGAWYK | ESELCKRAGI | FSASGLVGTM | FAGYLQTAVH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SSLNGKGGLS | GWRWLFIIDG | ILTIPLSLYG | LFLFPDVPET | TKAPYFTEQE | KELSFKRLPA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RPKKKPLTLK | AIKDIVRSWR | IYGLCILWIF | SGETQAIAVN | VLMGQWMKWS | NKFSVAQINN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YPTVITAVGV | VSTLGASVIS | DKLAGNPRWP | FGLFLCVITT | VSATILLAWN | VPDGAKFFAY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| FASGCTYAGQ | AVWFSWANDI | CRDNDQERGV | VVFLMNMCQN | IWHIWWAPIM | YPNTDTPRFI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KGLIGLLVVG | GIVFVSSCIV | SYMQIRDKRI | KRSIQDAKDF | DDVFTEHESL | ELKKIGKNDE |
| 490 | 500 | 510 | |||
| ESLNTTNAVK | EISSPGLVIT | RQRISMPKET | NAQD |