O42996
Gene name |
pi073 (SPBC27B12.05) |
Protein name |
Uncharacterized WD repeat-containing protein C27B12.05 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPBC27B12.05 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O42996
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O42996-F1 | Predicted | AlphaFoldDB |
No variants for O42996
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for O42996 | |||||
No associated diseases with O42996
11 regional properties for O42996
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PB1 domain | 12 - 95 | IPR000270 |
| domain | Protein kinase domain | 253 - 522 | IPR000719 |
| domain | AGC-kinase, C-terminal | 524 - 595 | IPR000961 |
| domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | 127 - 179 | IPR002219 |
| active_site | Serine/threonine-protein kinase, active site | 373 - 385 | IPR008271 |
| binding_site | Protein kinase, ATP binding site | 259 - 286 | IPR017441 |
| domain | Protein kinase, C-terminal | 544 - 585 | IPR017892 |
| domain | Diacylglycerol/phorbol-ester binding | 125 - 139 | IPR020454-1 |
| domain | Diacylglycerol/phorbol-ester binding | 141 - 150 | IPR020454-2 |
| domain | Diacylglycerol/phorbol-ester binding | 154 - 165 | IPR020454-3 |
| domain | Diacylglycerol/phorbol-ester binding | 166 - 178 | IPR020454-4 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| nonfunctional rRNA decay | An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQRDLTVDEF | LNYLYINVKE | LFTLKEKSFH | FWRNSLISCS | KTKNFLFVVV | GDEVLVYDLK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EISSDASEPE | PCFYLHCPHE | ASSSRQGDIN | QDMPNVINNV | RCELIGDLEY | FITANDCGKV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIYDVQKLNR | EPIIYDVQHS | AWGLAVSPLR | ILGISSNSHN | VNLFHLSPEF | KRFKEDYHSP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WFRQETLVLE | GHEHNIPCIT | FNSSGTLLLS | GSIDRSLQIW | DITSLSCLCK | FYTKLSIWGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KFIDKNAFYH | ISILKHKPGS | LIPAQQFGQS | PWKPPIMSSS | AFLLSHEEDF | DDDAVFEGEY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YVHIQDELPK | TKVKNYFRTY | LRQKPEELFI | FTTKFSIVLC | AYMGNSQIFP | LVSSKNCFEE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PITPRFQALH | RINMIECIPE | LQSVVCASQS | GQLTLLRLIC | TTKILNGNPI | YVYSFVPHKI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| RLTHLVDAPL | LGMSVCPLYP | GEENPFKRFK | IMLTVYTGKV | ISVEVQLSEN | LYDTSHIGNI |
| PL |