O42933

PR
Gene name
ogm4 (oma4, SPBC16C6.09)
Protein name
Dolichyl-phosphate-mannose--protein mannosyltransferase 4
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC16C6.09
EC number
2.4.1.109: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O42933

Entry ID Method Resolution Chain Position Source
AF-O42933-F1 Predicted AlphaFoldDB

No variants for O42933

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O42933

No associated diseases with O42933

3 regional properties for O42933

Type Name Position InterPro Accession
domain Glycosyl transferase family 39/83 64 - 309 IPR003342
domain MIR motif 336 - 514 IPR016093
domain Protein O-mannosyl-transferase, C-terminal four TM domain 549 - 770 IPR032421

Functions

Description
EC Number 2.4.1.109 Hexosyltransferases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
dolichyl-phosphate-mannose-protein mannosyltransferase activity Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.

2 GO annotations of biological process

Name Definition
cell wall mannoprotein biosynthetic process The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
protein O-linked mannosylation The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASKSEKAVK KAQKLSKEPS VELTDTKSSD NVTPKQKSPN STEEDVSLNL KTLKAKKFKL
70 80 90 100 110 120
AFVLITVLSF ITRFWNLNLP GEVVFDEVHF GKFASYYLQG KYFFDLHPPF AKLLLALVAK
130 140 150 160 170 180
LAGYDGHYLF DNIGDNYKDN GVPYVTIRAW PALLSSLVPP VVFLIMKESG YDLLACIVSS
190 200 210 220 230 240
SLVLFDNAHV TEGRLILLDA TLLFSMVCAI YCYVRFFKLR HTPFSRPWWA WLFFTGFFLS
250 260 270 280 290 300
CTISTKYVGF FTFLSIGLSV CLELWYLWDI KTGLTVERFF QHFLARFFCL IFFPFLFFLF
310 320 330 340 350 360
WFYMHFNILT ISGPGDSFMS LEFQETLSDN PITANSTILN YYDIVTIKHM GTNAFLHSHP
370 380 390 400 410 420
EKYPIPYDDG RISSGGQQVT GYQFDDENNY WMILPADHYD PPIEAKLNVP VKNMDYIKLH
430 440 450 460 470 480
HVGTNTDLMT HDVASPYHPT NEEFTTVSVD ESAGKKHEYT LFQVVMSDNT DPQRPLYTKA
490 500 510 520 530 540
SSFKLIHKLT HVAMWSDPKP LPDWAFKQLE INGAKNIQTG SIFWTFDDII GLKDSRLKKE
550 560 570 580 590 600
KKIPKKLPFW KKYLELQLTM FRQNNMLTEF HPYSSNPSDW FTLHHGIAFW AKSEENKQIY
610 620 630 640 650 660
LLGNPIGWWI IAGTVLSTTV VAAAEILLRQ RGIRTLPETV RNHFYRSTMF FYMTYVFHYL
670 680 690 700 710 720
PFFIMGRQLF LHHYLPAHLA GSLLVGAFIQ LACRKSFRSP VSAGVPIPKD VDEKGHSKCH
730 740 750 760 770
RKYGHVIELI CTLLLIFVVI YCFTFFAPMT YGDKSLSVDE WTRRKWLDSW VFQYQKQN