Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for O42266

Entry ID Method Resolution Chain Position Source
AF-O42266-F1 Predicted AlphaFoldDB

No variants for O42266

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O42266

No associated diseases with O42266

2 regional properties for O42266

Type Name Position InterPro Accession
conserved_site Membrane attack complex component/perforin domain, conserved site 195 - 206 IPR020863
domain Membrane attack complex component/perforin (MACPF) domain 23 - 340 IPR020864

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
photoreceptor activity The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.

2 GO annotations of biological process

Name Definition
phototransduction The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
visual perception The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASIILINFS ETDTLHLGSV NDHIMPRIGY TILSIIMALS STFGIILNMV VIIVTVRYKQ
70 80 90 100 110 120
LRQPLNYALV NLAVADLGCP VFGGLLTAVT NAMGYFSLGR VGCVLEGFAV AFFGIAGLCS
130 140 150 160 170 180
VAVIAVDRYM VVCRPLGAVM FQTKHALAGV VFSWVWSFIW NTPPLFGWGS YQLEGVMTSC
190 200 210 220 230 240
APNWYRRDPV NVSYILCYFM LCFALPFATI IFSYMHLLHT LWQVAKLQVA DSGSTAKVEV
250 260 270 280 290 300
QVARMVVIMV MAFLLTWLPY AAFALTVIID SNIYINPVIG TIPAYLAKSS TVFNPIIYIF
310 320 330 340
MNRQFRDYAL PCLLCGKNPW AAKEGRDSDT NTLTTTVSKN TSVSPL