O42154

PR
Gene name
g6pc1 (g6pc, g6pt)
Protein name
Glucose-6-phosphatase catalytic subunit 1
Names
Glucose-6-phosphatase, G-6-Pase, G6Pase
Species
Haplochromis xenognathus (Lake Victoria cichlid) (Ptyochromis xenognathus)
KEGG Pathway
EC number
3.1.3.9: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O42154

Entry ID Method Resolution Chain Position Source
AF-O42154-F1 Predicted AlphaFoldDB

No variants for O42154

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O42154

No associated diseases with O42154

1 regional properties for O42154

Type Name Position InterPro Accession
domain Phosphatidic acid phosphatase type 2/haloperoxidase 1 - 117 IPR000326

Functions

Description
EC Number 3.1.3.9 Phosphoric monoester hydrolases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
glucose-6-phosphatase activity Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.

1 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
FGERPYWWVH ETKFYGAGPA PSLQQFPITC ETGPGSPSGH AMGAAGVWYV MVTALLSIAR
70 80 90 100 110 120
EKQCPPLLYR FLYIGLWMLM GLVELVVCIS RVYMAAHFPH QVIAGIITGT LVAEVVSKEK
130 140 150 160 170 180
WIYSASLKKY FLITLFLTSF AVGFYVLLKA LDVDLLWTME KAQKWCIRPE WVHLDSAPFA
190 200 210 220 230 240
SLLRNMGSLF GLGLGLHSPF YKTTKMRIMS APLRIGCIVI SVSLLHLLDG WTFSPENHMT
250 260 270
FYALSFGKSA VALLIPTTLV PWALSKIYPV KTEGKNL