O42153

PR
Gene name
g6pc1 (g6pc, g6pt)
Protein name
Glucose-6-phosphatase catalytic subunit 1
Names
Glucose-6-phosphatase, G-6-Pase, G6Pase
Species
Haplochromis nubilus (Blue Victoria mouthbrooder) (Tilapia nubila)
KEGG Pathway
EC number
3.1.3.9: Phosphoric monoester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

68-140 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O42153

Entry ID Method Resolution Chain Position Source
AF-O42153-F1 Predicted AlphaFoldDB

No variants for O42153

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O42153

No associated diseases with O42153

1 regional properties for O42153

Type Name Position InterPro Accession
domain Phosphatidic acid phosphatase type 2/haloperoxidase 54 - 192 IPR000326

Functions

Description
EC Number 3.1.3.9 Phosphoric monoester hydrolases
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
glucose-6-phosphatase activity Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.

1 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDLLHSWGVE LAVYLQTRYG KYEGLFDLAS TVADLHTTFF WLFPIWFHLR RDTALRLIWV
70 80 90 100 110 120
AVIGDWLNLV LKWVLFGERP YWWVHETKFY GAGPAPSLQQ FPITCETGPG SPSGHAMGAA
130 140 150 160 170 180
GVWYVMVTAL LSIAREKQCP PLLYRFLYIG LWMLMGLVEL VVCISRVYMA AHFPHQVIAG
190 200 210 220 230 240
IITGTLVAEV VSKEKWIYSA SLKKYFLITL FLTSFAVGFY VLLKALDVDL LWTMEKAQKW
250 260 270 280 290 300
CIRPEWVHLD SAPFASLLRN MGSLFGLGLG LHSPFYKTTK MRIMSAPLRI GCIVISVSLL
310 320 330 340 350
HLLDGWTFSP ENHMTFYALS FGKSAVALLI PTTLVPWALS KIYPVKTEGK NL