O36033

PR
Gene name
SPAC19B12.01 (SPAC4F10.21)
Protein name
TPR repeat-containing protein C19B12.01
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC19B12.01
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

208-328 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O36033

Entry ID Method Resolution Chain Position Source
AF-O36033-F1 Predicted AlphaFoldDB

12 variants for O36033

Variant ID(s) Position Change Description Diseaes Association Provenance
I_4875578_G_A 2 V>I No Jeffares_SNPs
I_4875581_G_A 3 A>T No Jeffares_SNPs
I_4875809_G_A 79 E>K No Jeffares_SNPs
I_4875838_C_A 88 D>E No Jeffares_SNPs
I_4876073_G_A 167 V>M No Jeffares_SNPs
I_4876077_G_A 168 S>N No Jeffares_SNPs
I_4876121_A_G 183 T>A No Jeffares_SNPs
I_4876415_G_A 281 A>T No Jeffares_SNPs
I_4876474_A_C 300 K>N No Jeffares_SNPs
I_4876592_T_C 340 Y>H No Jeffares_SNPs
I_4877087_A_G 505 N>D No Jeffares_SNPs
I_4877836_G_C 754 E>D No Jeffares_SNPs

No associated diseases with O36033

2 regional properties for O36033

Type Name Position InterPro Accession
repeat Tetratricopeptide repeat 521 - 554 IPR019734-1
repeat Tetratricopeptide repeat 555 - 588 IPR019734-2

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVAIENKEVL FGGSLKSTEE YDQFFCPSID IPKFLFKYWD SKPLGKNVSS DQFAETAIQM
70 80 90 100 110 120
LEYFIQNNYT GPYLPIKPEI WLPQRLRDEA TLKDAIIKSL TVEGERPYRL APKLLFLLLS
130 140 150 160 170 180
QTLFNYANSK DPLHIWYKAR LDFLHQQMLK EHVSELFNQI MEGMHIVSSH VSSLDRDLQG
190 200 210 220 230 240
RFTMEMGLIQ SYYGRDTLAL QLMKESAKVM DFHFELTGAL GRRTKFQTFD TSQLVVLAKS
250 260 270 280 290 300
RDRCKDTEQN KSTSTQPITF ELNDDTLLEK ISFKEDQKSL APSEELDPIL SSEDPNHPSK
310 320 330 340 350 360
LDPLDASLLL AFCHIIKNNN PDDGLTREEM APYAERVLVY PVNWSVYTMA LLVRARLEGF
370 380 390 400 410 420
KSRTVERSVL QMQALLDQLN DQLSFGKSPE GVDKPENDEG LGSFLPKPQD GENSASLKER
430 440 450 460 470 480
LNYFYNLLMP SRWQLEAELA ERFISVGATK SALEIFERLQ MWDCVVMCHC SLNRQDLAVQ
490 500 510 520 530 540
VIKRELENDP YDFLLRTLLG DIENNPKHYV EAWELSCKRF APAQRSLGKY YYKKGDLLQA
550 560 570 580 590 600
MNCFNESLKI NPLSYPTWFT YGCAALELQK YDAAMEAFSR CLSINPEDGE SWNNLASAML
610 620 630 640 650 660
KAKDHTKEQA WHAMQQGIKY MYDNWRIWEN YMLISVDVNK WSEVIRALRR IIEIKGKDEG
670 680 690 700 710 720
ERAVDVQCLD LVVNYVMQSC DNDASGLARM LNELLKMVVP LITNDVRLWR IVARYYLWRR
730 740 750 760 770 780
HFAESLNATL KAYRILISSP NVTSDEATWN KTVEGALELV EAYANLGEMP GRMGGVVAKD
790 800 810
WKFKSRSVLR SLIGKGKNIW ENTESYQKLE SELENLK