O36022
Gene name |
mnn9 |
Protein name |
Mannan polymerase complex subunit mnn9 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC4F10.10c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O36022
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O36022-F1 | Predicted | AlphaFoldDB |
1 variants for O36022
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_4851315_C_T | 3 | V>M | No | Jeffares_SNPs |
No associated diseases with O36022
4 regional properties for O36022
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | MoaA/NifB/PqqE, iron-sulphur binding, conserved site | 20 - 31 | IPR000385 |
| domain | Elp3/MiaA/NifB-like, radical SAM core domain | 14 - 226 | IPR006638 |
| domain | Radical SAM | 8 - 234 | IPR007197 |
| domain | Molybdenum cofactor biosynthesis protein A-like, twitch domain | 186 - 321 | IPR010505 |
Functions
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| mannan polymerase complex | A protein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins. |
| mannan polymerase II complex | A complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins as part of the elongation of alpha 1,6-linked Man backbone. In S. cerevisiae, contains Mnn9p, Anp1p, Mnn10p, Mnn11p, and Hoc1p. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mannosyltransferase activity | Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cell wall mannoprotein biosynthetic process | The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues. |
| protein N-linked glycosylation | A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRVYNKSRIV | GQLLFVALGI | TFIYYLFTPS | VNSNAKVQIE | NRGGNSYEIY | DMNKITESSD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PIRNKEEVLI | LTPIARFYPQ | YWKNLLELDY | PRNLISLGFI | VPSSKDGAKV | HRELRNAINA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VQKGPGDKRF | ADVKILIQDS | DLSSGQSEAE | RHKFSAQKER | RGKLAATRNT | LLLSTLKPST |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SWVLWLDSDI | VETPSTLIQD | LAEHNEDVLV | ANCFQKQGDK | LTPYDFNSWV | DSQTAQELAS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HMDRDEILLE | GYAELPTYRM | LMAKIYEEHK | DPSTIMALDG | VGTTALLVKA | SVHRDGALFP |
| 310 | 320 | 330 | |||
| TFPFYHLIES | EGFAKMAKRL | GHGVYGLPYY | LVFHHNE |