O35156
Gene name |
UGP2 (UGP1) |
Protein name |
UTP--glucose-1-phosphate uridylyltransferase |
Names |
UDP-glucose pyrophosphorylase, UDPGP, UGPase |
Species |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) |
KEGG Pathway |
cge:100689325 |
EC number |
2.7.7.9: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for O35156
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-O35156-F1 | Predicted | AlphaFoldDB |
1 variants for O35156
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 116 | G>D | Don Q cell line; low level of activity [UniProt] | No |
No associated diseases with O35156
No regional properties for O35156
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for O35156 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.9 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| identical protein binding | Binding to an identical protein or proteins. |
| metal ion binding | Binding to a metal ion. |
| UTP:glucose-1-phosphate uridylyltransferase activity | Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| brain development | The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). |
| glycogen biosynthetic process | The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. |
| UDP-glucose metabolic process | The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSRFVQDLSK | AMSQDGASQF | QEVILQELEL | SVKKELEKIL | TTATSHEYEH | TKKDLDGFRK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LYHRFLQEKG | PSVDWGKIQR | PPEDSIQPYE | KIKARGLPDN | ISSVLNKLVV | VKLNGGLGTS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MGCKGPKSLI | GVRNENTFLD | LTVQQIEHLN | KSYNTDVPLV | LMNSFNTDED | TKKILQKYNH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| CRVKIYTFNQ | SRYPRINKES | LLPVAKDVSS | SGESTEAWYP | PGHGDIYASF | YNSGLLDTFL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EEGKEYIFVS | NIDNLGATVD | LYILNHLMNP | PNGKRCEFVM | EVTNKTRADV | KGGTLTQYEG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KLRLVEIAQV | PKAHVDEFKS | VSKFKIFNTN | NLWISLAAVK | RLQEQNAIDM | EIIVNPKTLD |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GGLNVIQLET | AVGAAIKSFE | NSLGINVPRS | RFLPVKTTSD | LLLVMSNLYS | LNAGSLTMSE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KREFPTVPLV | KLGSSFTKVQ | DYLRRFESIP | DMLELDHLTV | SGDVTFGKNV | SLKGTVIIIA |
| 490 | 500 | ||||
| NHGDRIDIPP | GAVLENKIVS | GNLRILDH |