Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

7 structures for O35044

Entry ID Method Resolution Chain Position Source
8G3A EM 340 A D/E 1-334 PDB
8G3B EM 350 A D/E 1-334 PDB
8G3F EM 370 A D/E 1-334 PDB
8G3L EM 350 A D/E 1-334 PDB
8G4C EM 310 A D/E 1-334 PDB
8G4D EM 360 A D/E 1-334 PDB
AF-O35044-F1 Predicted AlphaFoldDB

No variants for O35044

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O35044

No associated diseases with O35044

No regional properties for O35044

Type Name Position InterPro Accession
No domain, repeats, and functional sites for O35044

Functions

Description
EC Number 2.7.13.3 Protein-histidine kinases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein histidine kinase activity Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.

1 GO annotations of biological process

Name Definition
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIKAFLIERR SWIAAFLFQQ ALMLFIAFVD PSISFGNVLY MVYLCILFFI IFLWFRYRKE
70 80 90 100 110 120
TAFYKSLKTW ENNLDVTAIN EPETPFEAMV ERSIAGQTEH LKQTAARHRL ALENEKDELM
130 140 150 160 170 180
AWIHEVKTPL TAMHLIIDRM EEKALKSQLS YEWLRIHLLL DQQLHQKRIS FIENDLSVEF
190 200 210 220 230 240
IQLQPLIFKE IKDLQSWCIQ KGIGFDIQLE AKEVLSDAKW LAFIIRQLLT NAVKYSEASE
250 260 270 280 290 300
IEIKSFQKGE QTQLQVKDCG RGIDPKDVPR IFDKGFTSTT DHHDQASTGM GLYLAKKAAA
310 320 330
PLLIHIDVES EFGAGTVFTL TFPIRNQFEH VISV