O34835

PR
Gene name
fapR (ylpC, BSU15880)
Protein name
Transcription factor FapR
Names
Fatty acid and phospholipid biosynthesis regulator
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU15880
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-95 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for O34835

Entry ID Method Resolution Chain Position Source
2F3X X-ray 310 A A/B 44-188 PDB
2F41 X-ray 250 A A/B/C/D 68-188 PDB
AF-O34835-F1 Predicted AlphaFoldDB

No variants for O34835

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O34835

No associated diseases with O34835

1 regional properties for O34835

Type Name Position InterPro Accession
domain Thioesterase domain 107 - 166 IPR006683

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

3 GO annotations of biological process

Name Definition
fatty acid biosynthetic process The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
negative regulation of fatty acid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRRNKRERQE LLQQTIQATP FITDEELAGK FGVSIQTIRL DRLELSIPEL RERIKNVAEK
70 80 90 100 110 120
TLEDEVKSLS LDEVIGEIID LELDDQAISI LEIKQEHVFS RNQIARGHHL FAQANSLAVA
130 140 150 160 170 180
VIDDELALTA SADIRFTRQV KQGERVVAKA KVTAVEKEKG RTVVEVNSYV GEEIVFSGRF
DMYRSKHS