O34824

PR
Gene name
glmM
Protein name
Phosphoglucosamine mutase
Names
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU01770
EC number
5.4.2.10: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

90-242 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for O34824

Entry ID Method Resolution Chain Position Source
7OJR X-ray 305 A A 1-448 PDB
7OJS X-ray 420 A A/B/C/F/G/J 1-369 PDB
7OLH X-ray 365 A A/B/C/D/E/F 1-448 PDB
7OML X-ray 290 A A 1-448 PDB
AF-O34824-F1 Predicted AlphaFoldDB

No variants for O34824

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O34824

No associated diseases with O34824

5 regional properties for O34824

Type Name Position InterPro Accession
domain Alpha-D-phosphohexomutase, C-terminal 373 - 441 IPR005843
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain I 3 - 134 IPR005844
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain II 158 - 253 IPR005845
domain Alpha-D-phosphohexomutase, alpha/beta/alpha domain III 257 - 368 IPR005846
conserved_site Alpha-D-phosphohexomutase, conserved site 94 - 103 IPR016066

Functions

Description
EC Number 5.4.2.10 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
magnesium ion binding Binding to a magnesium (Mg) ion.
phosphoglucosamine mutase activity Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.
phosphomannomutase activity Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
peptidoglycan biosynthetic process The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
UDP-N-acetylglucosamine biosynthetic process The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGKYFGTDGV RGVANSELTP ELAFKVGRFG GYVLTKDKQR PKVLIGRDTR ISGHMLEGAL
70 80 90 100 110 120
VAGLLSIGAE VMRLGVISTP GVSYLTKAMD AEAGVMISAS HNPVQDNGIK FFGGDGFKLS
130 140 150 160 170 180
DEQEAEIERL MDEPEDKLPR PVGADLGLVN DYFEGGQKYL QFLKQTADED FTGIHVALDC
190 200 210 220 230 240
ANGATSSLAT HLFADLDADV STMGTSPNGL NINDGVGSTH PEALSAFVKE KNADLGLAFD
250 260 270 280 290 300
GDGDRLIAVD EKGNIVDGDQ IMYICSKHLK SEGRLKDDTV VSTVMSNLGF YKALEKEGIK
310 320 330 340 350 360
SVQTAVGDRY VVEAMKKDGY NVGGEQSGHL IFLDYNTTGD GLLSAIMLMN TLKATGKPLS
370 380 390 400 410 420
ELAAEMQKFP QLLVNVRVTD KYKVEENEKV KAVISEVEKE MNGDGRILVR PSGTEPLVRV
430 440
MAEAKTKELC DEYVNRIVEV VRSEMGLE