O34453

PR
Gene name
nos (yflM, BSU07630)
Protein name
Nitric oxide synthase oxygenase
Names
NOSoxy-like protein
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU07630
EC number
1.14.14.47: With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

276-350 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

85 structures for O34453

Entry ID Method Resolution Chain Position Source
1M7V X-ray 195 A A 5-363 PDB
1M7Z X-ray 214 A A 5-363 PDB
2AMO X-ray 260 A A/B 30-363 PDB
2AN0 X-ray 260 A A 6-363 PDB
2AN2 X-ray 260 A A 6-363 PDB
2FBZ X-ray 210 A X 5-363 PDB
2FC1 X-ray 200 A A 5-363 PDB
2FC2 X-ray 220 A A/B 5-363 PDB
4D3I X-ray 209 A A 1-363 PDB
4D3J X-ray 167 A A 1-363 PDB
4D3K X-ray 202 A A/B 1-363 PDB
4D3M X-ray 174 A A 1-363 PDB
4D3N X-ray 213 A A 1-363 PDB
4D3O X-ray 190 A A 1-363 PDB
4D3T X-ray 155 A A 1-363 PDB
4D3U X-ray 198 A A 1-363 PDB
4D3V X-ray 188 A A 1-363 PDB
4D7H X-ray 202 A A 1-363 PDB
4D7I X-ray 196 A A 1-363 PDB
4D7J X-ray 155 A A 1-363 PDB
4LWA X-ray 206 A A 1-363 PDB
4LWB X-ray 215 A A 1-363 PDB
4UG5 X-ray 235 A A 1-363 PDB
4UG6 X-ray 181 A A 1-363 PDB
4UG7 X-ray 176 A A 1-363 PDB
4UG8 X-ray 189 A A 1-363 PDB
4UG9 X-ray 184 A A 1-363 PDB
4UGA X-ray 190 A A 1-363 PDB
4UGB X-ray 191 A A 1-363 PDB
4UGC X-ray 180 A A 1-363 PDB
4UGD X-ray 203 A A 1-363 PDB
4UGE X-ray 214 A A 1-363 PDB
4UGF X-ray 181 A A 1-363 PDB
4UGG X-ray 236 A A 1-363 PDB
4UGH X-ray 199 A A 1-363 PDB
4UGI X-ray 180 A A 1-363 PDB
4UGJ X-ray 178 A A 1-363 PDB
4UGK X-ray 162 A A 1-363 PDB
4UGL X-ray 182 A A 1-363 PDB
4UGM X-ray 209 A A 1-363 PDB
4UGN X-ray 209 A A 1-363 PDB
4UGO X-ray 238 A A 1-363 PDB
4UGP X-ray 180 A A 1-363 PDB
4UGQ X-ray 185 A A 1-363 PDB
4UGR X-ray 209 A A 1-363 PDB
4UGS X-ray 199 A A 1-363 PDB
4UGT X-ray 203 A A 1-363 PDB
4UGU X-ray 180 A A 1-363 PDB
4UGV X-ray 199 A A 1-363 PDB
4UGW X-ray 190 A A 1-363 PDB
4UGX X-ray 186 A A 1-363 PDB
4UGY X-ray 180 A A 1-363 PDB
4UQR X-ray 172 A A 1-363 PDB
4UQS X-ray 215 A A 1-363 PDB
5G65 X-ray 203 A A 1-363 PDB
5G66 X-ray 176 A A 1-363 PDB
5G67 X-ray 197 A A 1-363 PDB
5G68 X-ray 163 A A 1-363 PDB
5G69 X-ray 202 A A 1-363 PDB
5G6A X-ray 192 A A 1-363 PDB
5G6B X-ray 180 A A 1-363 PDB
5G6C X-ray 213 A A 1-363 PDB
5G6D X-ray 182 A A 1-363 PDB
5G6E X-ray 211 A A 1-363 PDB
5G6F X-ray 226 A A 1-363 PDB
5G6G X-ray 198 A A 1-363 PDB
5G6H X-ray 191 A A 1-363 PDB
5G6I X-ray 198 A A 1-363 PDB
5G6J X-ray 188 A A 1-363 PDB
5G6K X-ray 195 A A 1-363 PDB
5G6L X-ray 203 A A 1-363 PDB
5G6M X-ray 177 A A 1-363 PDB
5G6N X-ray 191 A A 1-363 PDB
5G6O X-ray 172 A A 1-363 PDB
5G6P X-ray 218 A A 1-363 PDB
5G6Q X-ray 203 A A 1-363 PDB
6XCX X-ray 225 A A 1-363 PDB
6XK3 X-ray 195 A A 1-363 PDB
6XK4 X-ray 213 A A 1-363 PDB
6XK5 X-ray 187 A A 1-363 PDB
6XK6 X-ray 184 A A 1-363 PDB
6XK7 X-ray 185 A A 1-363 PDB
6XK8 X-ray 225 A A 1-363 PDB
6XMC X-ray 185 A A 1-363 PDB
AF-O34453-F1 Predicted AlphaFoldDB

No variants for O34453

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O34453

No associated diseases with O34453

1 regional properties for O34453

Type Name Position InterPro Accession
domain Nitric oxide synthase, N-terminal 4 - 362 IPR004030

Functions

Description
EC Number 1.14.14.47 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.
nitric-oxide synthase activity Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.

1 GO annotations of biological process

Name Definition
nitric oxide biosynthetic process The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEEKEILWNE AKAFIAACYQ ELGKEEEVKD RLADIKSEID LTGSYVHTKE ELEHGAKMAW
70 80 90 100 110 120
RNSNRCIGRL FWNSLNVIDR RDVRTKEEVR DALFHHIETA TNNGKIRPTI TIFPPEEKGE
130 140 150 160 170 180
KQVEIWNHQL IRYAGYESDG ERIGDPASCS LTAACEELGW RGERTDFDLL PLIFRMKGDE
190 200 210 220 230 240
QPVWYELPRS LVIEVPITHP DIEAFSDLEL KWYGVPIISD MKLEVGGIHY NAAPFNGWYM
250 260 270 280 290 300
GTEIGARNLA DEKRYDKLKK VASVIGIAAD YNTDLWKDQA LVELNKAVLH SYKKQGVSIV
310 320 330 340 350 360
DHHTAASQFK RFEEQEEEAG RKLTGDWTWL IPPISPAATH IFHRSYDNSI VKPNYFYQDK
PYE