O34448

PR
Gene name
yopQ (BSU20800)
Protein name
SPbeta prophage-derived uncharacterized protein YopQ
Names
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU20800
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-57 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O34448

Entry ID Method Resolution Chain Position Source
AF-O34448-F1 Predicted AlphaFoldDB

No variants for O34448

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O34448

1 associated diseases with O34448

[MIM: 300310]: Immunodeficiency 61 (IMD61)

An X-linked recessive primary immunologic disorder characterized by recurrent infections due to impaired antibody production. Affected individuals have normal numbers of circulating B and T cells, but B cells have an intrinsic defect in antibody production. Disease severity is variable and onset is in early childhood. {ECO:0000269|PubMed:29636373}. Note=The disease may be caused by variants affecting the gene represented in this entry.

Without disease ID
  • An X-linked recessive primary immunologic disorder characterized by recurrent infections due to impaired antibody production. Affected individuals have normal numbers of circulating B and T cells, but B cells have an intrinsic defect in antibody production. Disease severity is variable and onset is in early childhood. {ECO:0000269|PubMed:29636373}. Note=The disease may be caused by variants affecting the gene represented in this entry.

6 regional properties for O34448

Type Name Position InterPro Accession
domain SH3 domain 1 - 58 IPR001452-1
domain SH3 domain 98 - 157 IPR001452-2
domain SH3 domain 267 - 328 IPR001452-3
domain SH3 domain-containing kinase-binding protein 1, first SH3 domain 3 - 55 IPR035770
domain SH3 domain-containing kinase-binding protein 1, second SH3 domain 102 - 154 IPR035771
domain SH3 domain-containing kinase-binding protein 1, third SH3 domain 271 - 326 IPR035772

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTVIFDQSAN EKLLSEMKDA ISKNKHIRSF INDIQLEMAK NKITPGTTQK LIYDIENPEV
70 80 90 100 110 120
EISKEYMYFL AKSLYSVLES ERFNPRNYFT ETDMREIETL WEGSVEEDIK FPYTFKQVVK
130 140 150 160 170 180
YSDDNYFFPI TAKELFMLFE NKLLHYNPNA QRTNKTKKLE GSDIEIPVPQ LNKQSVEEIK
190 200 210 220 230 240
ELFLDGKLIK SVFTFNARVG SASCGEELKY DDDTMSLTVT EDTILDVLDG YHRLIGITMA
250 260 270 280 290 300
IRQHPELDHL FEETFKVDIY NYTQKRAREH FGQQNTINPV KKSKVAEMSQ NVYSNKIVKF
310 320 330 340 350 360
IQDNSIIGDY IKTNGDWINQ NQNLLITFSD FKKAIERSYS KKDFSTQADI LKTARYLTSF
370 380 390 400 410 420
FDALATQYVD EFLGDIAKER KRSFVNNYLF FNGYVGLAKK LQLDGVSLDE LESKITDVLG
430 440 450
SIDFSKKNKL WDELGVVDKN GNAKSPQKIW NFFNNLKIDE