O34295

PR
Gene name
ttuC'
Protein name
Probable tartrate dehydrogenase/decarboxylase TtuC'
Names
TDH, D-malate dehydrogenase [decarboxylating]
Species
Agrobacterium vitis (Rhizobium vitis)
KEGG Pathway
EC number
1.1.1.83: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

221-300 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for O34295

Entry ID Method Resolution Chain Position Source
AF-O34295-F1 Predicted AlphaFoldDB

No variants for O34295

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for O34295

No associated diseases with O34295

2 regional properties for O34295

Type Name Position InterPro Accession
conserved_site Isocitrate/isopropylmalate dehydrogenase, conserved site 242 - 261 IPR019818
domain Isopropylmalate dehydrogenase-like domain 5 - 348 IPR024084

Functions

Description
EC Number 1.1.1.83 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

5 GO annotations of molecular function

Name Definition
D-malate dehydrogenase (decarboxylating) activity Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate.
magnesium ion binding Binding to a magnesium (Mg) ion.
NAD binding Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
tartrate decarboxylase activity Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2).
tartrate dehydrogenase activity Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MREYKIAAIP ADGIGPEVIA AGLQVLEALE QRSGDFKIHT ETFDWGSDYY KKHGVMMPAD
70 80 90 100 110 120
GLDKLKKFDA IFFGAVGAPD VPDHITLWGL RLPICQGFDQ YANVRPTKIL PGITPPLRNC
130 140 150 160 170 180
GPGDLDWVIV RENSEGEYSG HGGRAHRGLP EEVGTEVAIF TRVGVTRIMR YAFKLAQARP
190 200 210 220 230 240
RKLLTVVTKS NAQRHGMVMW DEIAAEVATE FPDVTWDKML VDAMTVRMTL KPETLDTIVA
250 260 270 280 290 300
TNLHADILSD LAGALAGSLG VAPTANIDPE RRFPSMFEPI HGSAFDITGK GIANPIATFW
310 320 330 340 350
TAAQMLEHLG ERDAAARLMG AVERVTEAGI LTPDVGGTAN TSQVTEAVCN AIAGSNII